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Es un cambio en la localización. Generalmente se refiere a translocaciones genéticas, en las cuales parte de un cromosoma se transfiere a otro cromosoma. Este tipo de translocación produce cromosomas modificados y con frecuencia defectuosos. En otro tipo de translocación, dos cromosomas intercambiarán partes entre sí.
Las translocaciones genéticas pueden causar trastornos graves, entre ellos, un tipo de leucemia mielógena crónica.
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