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Hemólisis - Overview

Overview

Definición:

Es la descomposición de los glóbulos rojos.

Ver también: anemia hemolítica.

Información:

Los glóbulos rojos viven normalmente de 110 a 120 días. Después de esto, se descomponen de manera natural y generalmente son eliminados de la circulación por medio del bazo.

Algunas enfermedades y procesos provocan que los glóbulos rojos se descompongan demasiado pronto. Esto le exige a la médula ósea producir más glóbulos rojos de lo normal. El equilibrio entre la descomposición y la producción de los glóbulos rojos determina qué tan bajo llega ser su conteo.

Las enfermedades que pueden causar hemólisis comprenden:

Reacciones inmunitarias
Infecciones
Medicamentos
Toxinas y venenos
Tratamientos como la hemodiálisis o el uso del sistema de circulación extracorporal

Reviewed last on: 1/31/2010
Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Scwartz RS. Autoimmune and intravascular hemolytic anemias. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 164.

Gregg XT, Prchal JT. Red blood cell enzymopathies. In: Hoffman R, Benz EJ, Shattil SS, et al., eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 45.

Gallagher PG, Jarolim P. Red blood cell membrane disorders. In: Hoffman R, Benz EJ, Shattil SS, et al., eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 46.

Powers A, Silberstein LE. Autoimmune hemolytic anemia. In: Hoffman R, Benz EJ, Shattil SS, et al., eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 47.

Schrier Sl, Price EA. Extrinsic nonimmune hemolytic anemias. In: Hoffman R, Benz EJ, Shattil SS, et al., eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 48.

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