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Colinesterasa en la sangre - Overview

Nombres alternativos

Acetilcolinesterasa; Colinesterasa en glóbulos rojos sanguíneos (o eritrocitos); Seudocolinesterasa; Colinesterasa en plasma; Butirilcolinesterasa; Colinesterasa sérica

Definición:

Es un examen de sangre con el cual se analizan los niveles de dos sustancias, llamadas acetilcolinesterasa y seudocolinesterasa, que ayudan al sistema nervioso a trabajar apropiadamente. Los nervios necesitan estas sustancias para enviar señales.

La acetilcolinesterasa se encuentra en el tejido nervioso y en los glóbulos rojos, mientras que la seudocolinesterasa se encuentra principalmente en el hígado.

Forma en que se realiza el examen:

Se necesita una muestra de sangre. Para obtener información sobre la forma como se hace esto, ver el artículo: venopunción .

Preparación para el examen:

No se requiere preparación especial para este examen.

Lo que se siente durante el examen:

Cuando se inserta la aguja para extraer la sangre, se puede sentir un dolor moderado o experimentar una sensación de pinchazo o picadura. Posteriormente, puede haber algo de sensación pulsátil.

Razones por las que se realiza el examen:

El médico posiblemente ordene este examen si usted puede haber estado expuesto a químicos llamados organofosfatos, los cuales se utilizan en pesticidas. Este examen puede ayudar a determinar el riesgo de intoxicación.

Con menor frecuencia, el examen se puede hacer:

  • Para diagnosticar enfermedad hepática.
  • Antes de recibir anestesia con succinilcolina, la cual se puede administrar antes de ciertos procedimientos o tratamientos, entre ellos, terapia electroconvulsiva (TEC).
  • Reviewed last on: 4/30/2011
  • Kevin Sheth, MD, Department of Neurology, University of Maryland School of Medicine, Baltimore, MD. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine;David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Ford MD. Acute poisoning. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier. 2007: chap 111.

Aminoff MJ. Effects of toxins and physical agents on the nervous system: effects of occupational toxins on the nervous system. In: Bradley WG, Daroff RB, Fenichel GM, Jankovic J, eds. Bradley: Neurology in Clinical Practice. 5th ed. Philadelphia, Pa: Butterworth-Heinemann Elsevier; 2008:chap 62A.

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