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Antígeno HLA-B27 - Results

Nombres alternativos

Antígeno leucocitario humano B27

Valores normales:

Un resultado normal (negativo) significa que el HLA-B27 está ausente.

Significado de los resultados anormales:

Un examen positivo significa que el HLA-B27 está presente y sugiere un riesgo mayor al promedio para desarrollar o tener ciertos trastornos autoinmunitarios. Un trastorno autoinmunitario es una afección que ocurre cuando el sistema inmunitario ataca por error y destruye el tejido sano del cuerpo.

Un resultado anormal puede ser causado por:

  • Espondilitis anquilosante
  • Artritis relacionada con enfermedad de Crohn
  • Artritis reactiva
  • Sacroileítis (inflamación de la articulación sacroilíaca)
  • Uveítis

Ante la presencia de síntomas, un examen positivo para HLA-B27 puede confirmar el diagnóstico. Sin embargo, el HLA-B27 normalmente se encuentra en un pequeño número de personas de raza blanca y no siempre significa que usted tenga una enfermedad.

  • Reviewed last on: 5/23/2011
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Miller FW. The spondyloarthropathies. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 286.

van der Linden SM, van der Heijde D, Maksymowych WP. Ankylosing spondylitis. In: Firestein GS, Budd RC, Harris ED, et al, eds. Kelley’s Textbook of Rheumatology. 8th ed. Philadelphia, Pa: Saunders Elsevier; 2009:chap 70.

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