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Examen VDRL en LCR - Overview

Nombres alternativos

Prueba serológica para sífilis (VDRL) en LCR

Definición:

Es una prueba que se usa para diagnosticar neurosífilis. Este examen busca la presencia de anticuerpos, llamados reaginas, que algunas veces son producidos por el cuerpo en reacción a la bacteria causante de la sífilis.

Ver también: prueba serológica para la sífilis (VDRL)

Forma en que se realiza el examen:

El examen se realiza generalmente en una muestra de líquido cefalorraquídeo (LCR) obtenida por punción lumbar (punción raquídea).

Preparación para el examen:

Antes del procedimiento, se le solicitará a la persona consultar sobre los riesgos y firmar una autorización.

Lo que se siente durante el examen:

Generalmente, la molestia asociada con la punción lumbar va de leve a moderada. El procedimiento total tarda usualmente alrededor de 30 minutos, aunque puede tomar más tiempo. La recolección real del líquido sólo toma unos cuantos minutos.

Razones por las que se realiza el examen:

El examen VDRL en LCR se emplea para diagnosticar sífilis en el cerebro o la médula espinal. El compromiso del cerebro y la médula espinal generalmente es indicio de la forma de la enfermedad en su etapa tardía (terciaria).

Los exámenes de sangre, como VDRL y RPR, son más efectivos durante la sífilis en su etapa intermedia (secundaria).

  • Reviewed last on: 7/27/2009
  • Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; and Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Redmond, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Hook EW III. Syphilis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 340.

Fletcher JJ, Nathan BR. Cerebrospinal fluid and intracranial pressure. In: Goetz, CG, eds. Textbook of Clinical Neurology. 3rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 26.

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