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Pregnanediol - Overview

Definición:

Es un producto activo que se forma cuando el cuerpo descompone la hormona progesterona. Se puede realizar un examen para medir la cantidad de pregnanediol en la orina. Dicho examen ofrece una forma indirecta de medir los niveles de progesterona en el cuerpo.

Forma en que se realiza el examen:

Se necesita una muestra de orina de 24 horas.

Preparación para el examen:

Es posible que el médico le solicite dejar de tomar ciertos medicamentos que pueden afectar el examen. Por ejemplo, la corticotropina puede incrementar las mediciones del examen, mientras que las píldoras anticonceptivas o la progesterona las pueden disminuir.

Lo que se siente durante el examen:

El examen involucra solamente el proceso normal de orinar y no se presenta ningún tipo de incomodidad.

Razones por las que se realiza el examen:

Antes de que hubiera disponibilidad de los exámenes de sangre para progesterona, este examen se utilizaba para vigilar embarazos y verificar posibles problemas con los ovarios o la corteza suprarrenal.

En las mujeres, la progesterona se produce principalmente después de que los ovarios liberan un óvulo (ovulación). La función principal de la progesterona es ayudar a preparar el útero para la posible implantación de un óvulo fecundado. Después de la fecundación, la progesterona es necesaria para la creación de la placenta, el órgano que se desarrolla para nutrir al feto. Durante el embarazo, la mayor parte de la progesterona es producida por la placenta.

La corteza suprarrenal también produce algo de progesterona. Ver: glándulas suprarrenales

Actualmente, este examen se usa muy poco excepto en los equipos caseros para predecir la ovulación.

  • Reviewed last on: 4/12/2009
  • Linda Vorvick, MD, Family Physician, Seattle Site Coordinator, Lecturer, Pathophysiology, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine; and Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Redmond, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Lobo RA. Reproductive endocrinology: neuroendocrinology, gonadotropins, sex steroids, prostaglandins, ovulation, menstruation, hormone assay. In: Katz VL, Lentz GM, Lobo RA, Gershenson DM, eds. Comprehensive Gynecology. 5th ed. Philadelphia, Pa: Mosby Elsevier; 2007:chap 4.

Lehmann HP, Henry JB. SI units. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 21st ed. Philadelphia, Pa: Saunders Elsevier; 2006:appendix 5.

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