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En muchos pacientes con miastenia grave, los músculos mejoran inmediatamente después de administrar el Tensilon, pero el beneficio máximo sólo dura unos pocos minutos. Para algunos tipos de miastenia, el Tensilon puede empeorar la debilidad.
Cuando la enfermedad empeora tanto que necesita tratamiento (crisis miasténica), hay una mejoría breve en la fuerza muscular.
Cuando hay una sobredosis de anticolinesterasa (crisis colinérgica), el Tensilon debilita aun más a la persona.
Sanders DB, Howard JF Jr. Disorders of neuromuscular transmission. In: Bradley WG, Daroff RB, Fenichel GM, Jankovic J, eds. Bradley: Neurology in Clinical Practice. 5th ed. Philadelphia, Pa: Butterworth-Heinemann Elsevier; 2008:chap 82.
Vincent A, Newsom-Davis J. Disorders of neuromuscular transmission. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 448.
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