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El principal nervio que baja por la pierna es el ciático. El dolor asociado con este nervio generalmente se origina en la parte superior a lo largo de la médula espinal cuando las raíces nerviosas se comprimen o dañan a causa del estrechamiento de la columna vertebral o por el desplazamiento de un disco. Los síntomas pueden incluir hormigueo, entumecimiento o dolor que se irradia a los glúteos, piernas y pies.
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