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Cuando se presenta un cáncer o una lesión en un lóbulo del pulmón, se recomienda la extirpación del lóbulo comprometido. Se hace una incisión entre las costillas para exponer el pulmón, mientras el paciente se encuentra bajo anestesia general, profundamente dormido y sin sentir dolor. Se examina la cavidad torácica y se extirpa el tejido del pulmón enfermo. Se inserta un tubo (sonda torácica) para drenar aire, fluidos y sangre de la cavidad torácica. Luego se suturan las costillas y la piel.

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