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En la mayoría de los casos, los divertículos pasan desapercibidos; sin embargo, pueden causar problemas en un porcentaje pequeño de pacientes. El problema más común es la diverticulitis, que ocurre cuando un pedazo pequeño y duro de heces queda atrapado en la cavidad del divertículo. Esto conduce a la inflamación y muerte de la sección del colon que contiene el divertículo.

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