Cardiovascular medications - ACE inhibitors
ACE inhibitor cardiovascular medications include:
- Benazepril (Lotensin)
- Captopril (Capoten and Capozide)
- Enalapril (Vasotec, Vasotec IV, and Vaseretic)
- Fosinopril (Monopril)
- Lisinopril (Prinivil, Zestril, Prinzide, and Zestoretic)
- Moexipril (Univasc and Uniretic)
- Perindopril Erbumine (Aceon)
- Quinapril (Accupril, Quinaretic, and Accuretic)
- Ramipril (Altace, Spirapril)
- Trandolapril (Mavik) calcemia
The use of captopril, fosinopril, or ramipril may cause depletion of sodium. Trandolapril may deplete sodium and calcium.
Calcium, along with vitamin D, keeps your bones strong and healthy.
Low levels of calcium may cause:
- Muscle cramps
- Numbness or tingling in toes and feet
- Irregular heartbeat
- Bone pain
- Spinal problems
Sodium deficiency is rare because it is widely available in dietary sources. When it does occur, low levels have been associated with:
- Nausea and vomiting
- Memory impairment
- Reduced attention
- Muscle cramps
- Strong, rapid or irregular heartbeat
- Lack of energy
Severe cases can cause seizures, loss of consciousness, and possibly coma. The development of symptoms depends on how fast you lose sodium.
The information presented here covers some of the nutrients that may be affected when you take certain medicines. If you have any of these signs and symptoms, it does not always mean you have low levels of these nutrients.
Factors that affect the level of nutrients are:
- Your medical history
- How long you have been taking the medicine
Please talk to your health care provider. They can best address your health care needs and see if you are at risk for low levels of any nutrients.
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Gold Standard Drug Database. Drug Monograph: Hydrochlorothiazide; Quinapril, 2016. www.clinicalkey.com/#!/content/drug_monograph/6-s2.0-2501. Accessed July 13, 2016.
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Smogorzewski MJ, Stubbs JR, Yu ASL. Disorders of calcium, magnesium, and phosphate balance. In: Skorecki K, Chertow GM, Marsden PA, Yu ASL, Taal MW, eds. Brenner and Rector's The Kidney. 10th ed. Philadelphia, PA: Elsevier; 2016:chap 19.
van Orten-Luiten AC, Janse A, Dhonukshe-Rutten RA, Witkamp RF. The association between drugs frequently used by the elderly and vitamin D blood levels: a review of observational and experimental studies. Drugs Aging. 2014;31(2):111-123. PMID: 24385337 www.ncbi.nlm.nih.gov/pubmed/24385337.
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- Last reviewed on 9/19/2016
- Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network. Also reviewed by the A.D.A.M. Editorial team.
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