Prednisone (By mouth)
Treats many diseases and conditions, especially problems related to inflammation. This medicine is a corticosteroid.
Rayos, predniSONE Intensol
When This Medicine Should Not Be Used
How to Use This Medicine
Liquid, Tablet, Delayed Release Tablet
- Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
- It is best to take this medicine with food or milk.
- Swallow the delayed-release tablet whole. Do not crush, break, or chew it.
- Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
- Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze the oral liquid.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Tell your doctor if you use any of the following:
- Aminoglutethimide, amphotericin B, carbamazepine, cholestyramine, cyclosporine, digoxin, isoniazid, ketoconazole, phenobarbital, phenytoin, or rifampin
- Blood thinner, such as warfarin
- NSAID pain or arthritis medicine, such as aspirin, diclofenac, ibuprofen, naproxen, celecoxib
- Diuretic (water pill)
- Diabetes medicine
- Macrolide antibiotic, such as azithromycin, clarithromycin, erythromycin
- Estrogen, including birth control pills or hormone replacement therapy
- This medicine may interfere with vaccines. Ask your doctor before you get a flu shot or any other vaccines.
Warnings While Using This Medicine
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding or if you have kidney problems, heart failure, high blood pressure, a recent heart attack, diabetes, glaucoma, osteoporosis, or thyroid problems. Tell your doctor about any infection you have. Also tell your doctor if you have had mental or emotional problems (such as depression) or stomach or bowel problems (such as an ulcer or diverticulitis).
- This medicine may cause the following problems:
- Mood or behavior changes
- Higher blood pressure, retaining water, changes in salt or potassium levels in your body
- Cataracts or glaucoma (with long-term use)
- Weak bones or osteoporosis (with long-term use)
- Slow growth in children (with long-term use)
- Muscle problems (with high doses, especially if you have myasthenia gravis or similar nerve and muscle problems)
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
- This medicine could cause you to get infections more easily. Tell your doctor right away if you are exposed to chicken pox, measles, or other serious infection. Tell your doctor if you had a serious infection in the past, such as tuberculosis or herpes.
- Tell your doctor about any extra stress or anxiety in your life. Your dose might need to be changed for a short time.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Dark freckles, skin color changes, coldness, weakness, tiredness, nausea, vomiting, weight loss
- Depression, unusual thoughts, feelings, or behaviors, trouble sleeping
- Fever, chills, cough, sore throat, and body aches
- Muscle pain or weakness
- Rapid weight gain, swelling in your hands, ankles, or feet
- Severe stomach pain, nausea, vomiting, or red or black stools
- Skin changes or growths
- Trouble seeing, eye pain, headache
If you notice these less serious side effects, talk with your doctor:
- Increased appetite
- Round, puffy face
- Weight gain around your neck, upper back, breast, face, or waist
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
- Last reviewed on 1/27/2017
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.