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Cardiovascular Disease Fellowship

Cardiology Faculty Publications 2008-Current

Preventive Cardiology | Atherosclerosis and Interventional Cardiology | Cardiomyopathy and Heart Transplantation | Echocardiography | Electrophysiology | Cardiovascular Science | Miscellaneous


Preventive Cardiology

  1. Kop WJ, Weissman NJ, Zhu J, Bonsall RW, Doyle M, Stretch MR, Glaes SB, Krantz DS, Gottdiener JS, Tracy RP.  Effects of acute mental stress and exercise on inflammatory markers in patients with coronary artery disease and healthy controls.   Am J Cardiol. 2008 Mar 15;101(6):767-73.

  2. Kop WJ, Weinstein AA, Deuster PA, Whittaker KS, Tracy RP. Inflammatory markers and negative mood symptoms following exercise withdrawal. Brain Behav Immun. 2008 Jul 9.

  3. Freedland KE, de Geus EJ, Golden RN, Kop WJ, Miller GE, Vaccarino V, Brumback B, Llabre MM, White VJ, Sheps DS. What's in a name? Psychosomatic medicine and biobehavioral medicine. Psychosom Med. 2009 Jan;71(1):1-4.

  4. Curtis LH, Hammill BG, Bethel MA, Anstrom KJ, Liao L, Gottdiener JS, Schulman KA. Pancreatic beta-cell function as a predictor of cardiovascular outcomes and costs: findings from the Cardiovascular Health Study.  Curr Med Res Opin. 2008 Jan;24(1):41-50.

  5. Asselbergs FW, Mozaffarian D, Katz R, Kestenbaum B, Fried LF, Gottdiener JS, Shlipak MG, Siscovick DS.  Association of renal function with cardiac calcifications in older adults: the cardiovascular health study. Nephrol Dial Transplant. 2008 Oct 7.

  6. Willke RJ, Zhou S, Vogel RA.  Differences in cardiovascular event rates between atorvastatin and simvastatin among new users: managed-care experience.  Curr Med Res Opin. 2008 Oct;24(10):2873-82.

  7. Miller M, Cannon C, Murphy SA, Qin J, Ray KK, Braunwald E, for the PROVE IT-TIMI 22 Investigators.  Impact of triglyceride levels beyond low density lipoprotein cholesterol after an acute coronary syndrome in the PROVE IT-TIMI 22 Trial.  J Am Coll Cardiol 2008; 51:724-730.

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Atherosclerosis and Interventional Cardiology

  1. Kop WJ, Weissman NJ, Zhu J, Bonsall RW, Doyle M, Stretch MR, Glaes SB, Krantz DS, Gottdiener JS, Tracy RP.  Effects of acute mental stress and exercise on inflammatory markers in patients with coronary artery disease and healthy controls.  Am J Cardiol. 2008 Mar 15;101(6):767-73.

  2. Kizer JR, Barzilay JI, Kuller LH, Gottdiener JS. Adiponectin and risk of coronary heart disease in older men and women.  J Clin Endocrinol Metab. 2008 Sep;93(9):3357-64.

  3. Poston RS, Tran R, Collins M, Reynolds M, Connerney I, Reicher B, Zimrin D, Griffith BP, Bartlett ST. Comparison of economic and patient outcomes with minimally invasive versus traditional off-pump coronary artery bypass grafting techniques. Ann Surg. 2008 Oct;248(4):638-46.

  4. Zimrin DA, Reyes PA, Miller KL, Fisher SD, Griffith BP, Gammie JS. Heart failure and "inoperable" aortic stenosis: staged balloon aortic valvuloplasty and aortic valve bypass. Congest Heart Fail. 2008 Jul-Aug;14(4):211-3.

  5. Reicher B, Poston RS, Mehra MR, Joshi A, Odonkor P, Kon Z, Reyes PA, Zimrin DA. Simultaneous "hybrid" percutaneous coronary intervention and minimally invasive surgical bypass grafting: feasibility, safety, and clinical outcomes. Am Heart J. 2008 Apr;155(4):661-7.

  6. Kon ZN, Brown EN, Tran R, Joshi A, Reicher B, Grant MC, Kallam S, Burris N, Connerney I, Zimrin D, Poston RS.    Simultaneous hybrid coronary revascularization reduces postoperative morbidity compared with results from conventional off-pump coronary artery bypass. J Thorac Cardiovasc Surg. 2008 Feb;135(2):367-75.

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Cardiomyopathy and Heart Transplantation

  1. Moran A, Katz R, Smith NL, Fried LF, Sarnak MJ, Seliger SL, Psaty B, Siscovick DS, Gottdiener JS, Shlipak MG.  Cystatin C concentration as a predictor of systolic and diastolic heart failure. J Card Fail. 2008 Feb;14(1):19-26.

  2. Rodondi N, Bauer DC, Cappola AR, Cornuz J, Robbins J, Fried LP, Ladenson PW, Vittinghoff E, Gottdiener JS, Newman AB.  Subclinical thyroid dysfunction, cardiac function, and the risk of heart failure. The Cardiovascular Health study.  J Am Coll Cardiol. 2008 Sep 30;52(14):1152-9.

  3. Mehra MR, Rockman HA, Greenberg BH.  Highlights of the 2008 Scientific Sessions of the Heart Failure Society of America. Toronto, Ontario, Canada, September 20-23, 2008.  J Am Coll Cardiol. 2009 Feb 10;53(6):514-22.

  4. Majeed F, Kop WJ, Poston RS, Kallam S, Mehra MR. Prospective, observational study of antiplatelet and coagulation biomarkers as predictors of thromboembolic events after implantation of ventricular assist devices.  Nat Clin Pract Cardiovasc Med. 2009 Feb;6(2):147-57

  5. Flaherty JD, Bax JJ, De Luca L, Rossi JS, Davidson CJ, Filippatos G, Liu PP, Konstam MA, Greenberg B, Mehra MR, Breithardt G, Pang PS, Young JB, Fonarow GC, Bonow RO, Gheorghiade M.  Acute heart failure syndromes in patients with coronary artery disease early assessment and treatment. Acute Heart Failure Syndromes International Working Group.  J Am Coll Cardiol. 2009 Jan 20;53(3):254-63.

  6. Rogers JS, Zakaria S, Thom KA, Flammer KM, Kanno M, Mehra MR.  Immune reconstitution inflammatory syndrome and human immunodeficiency virus-associated myocarditis. Mayo Clin Proc. 2008 Nov;83(11):1275-9.

  7. Shah KB, Kop WJ, Christenson RH, Diercks DB, Kuo D, Henderson S, Hanson K, Mehra MR, deFilippi CR. Lack of diagnostic and prognostic utility of circulating plasma myeloperoxidase concentrations in patients presenting with dyspnea.  Clin Chem. 2009 Jan;55(1):59-67.

  8. Greenberg B, Czerska B, Delgado RM, Bourge R, Zile MR, Silver M, Klapholz M, Haeusslein E, Mehra MR, Mather P, Abraham WT, Neaton JD, Brown BS, Parker IC, Konstam MA; MOMENTUM Investigators and Coordinators. Effects of continuous aortic flow augmentation in patients with exacerbation of heart failure inadequately responsive to medical therapy: results of the Multicenter Trial of the Orqis Medical Cancion System for the Enhanced Treatment of Heart Failure Unresponsive to Medical Therapy (MOMENTUM). Circulation. 2008 Sep 16;118(12):1241-9.

  9. Gottlieb SS.  Prognostic indicators: useful for clinical care? J Am Coll Cardiol. 2009 Jan 27;53(4):343-4.

  10. Gottlieb SS.  Adenosine A1 antagonists and the cardiorenal syndrome. Curr Heart Fail Rep. 2008 Jun;5(2):105-9.

  11. Nahm ES, Blum K, Scharf B, Friedmann E, Thomas S, Jones D, Gottlieb SS. Exploration of patients' readiness for an eHealth management program for chronic heart failure: a preliminary study. J Cardiovasc Nurs. 2008 Nov-Dec;23(6):463-71.

  12. Wang DJ, Gottlieb SS. Diuretics: still the mainstay of treatment. Crit Care Med. 2008 Jan;36(1 Suppl):S89-94.

  13. Rogers HL, Marshall J, Bock J, Dowling TC, Feller E, Robinson S, Gottlieb SS. A randomized, controlled trial of the renal effects of ultrafiltration as compared to furosemide in patients with acute decompensated heart failure. J Card Fail. 2008 Feb;14(1):1-5.

  14. O'Connell JB, McCarthy PM, Sopko G, Filippatos GS, Piña IL, Konstam MA, Young JB, Miller LW, Mehra MR, Roland E, Blair JE, Farrar DJ, Gheorghiade M.  Mechanical circulatory support devices for acute heart failure syndromes: considerations for clinical trial design.  Heart Fail Rev. 2008 Jun 12.

  15. Mehra MR, Reyes P, Benitez RM, Zimrin D, Gammie JS.Surgery for severe mitral regurgitation and left ventricular failure: what do we really know? J Card Fail. 2008 Mar;14(2):145-50.

  16. Mehra MR. The cardiac allograft is going up in smoke: a call to action. Am J Transplant. 2008 Apr;8(4):737-8.

  17. Mehra MR, Rockman HA, Greenberg BH.  Highlights of the 2007 Scientific Meeting of the Heart Failure Society of America: Washington, DC, September 16-19, 2007. J Am Coll Cardiol. 2008 Jan 22;51(3):320-7.

  18. Ramani GV, Bazaz R, Edelman K, López-Candales A.  Pulmonary hypertension affects left ventricular basal twist: a novel use for speckle-tracking imaging. Echocardiography. 2009 Jan;26(1):44-51. Epub 2008 Nov 19.

  19. Ramani GV, McCloskey C, Ramanathan RC, Mathier MA.  Safety and efficacy of bariatric surgery in morbidly obese patients with severe systolic heart failure. Clin Cardiol. 2008 Nov;31(11):516-20.

  20. Kochar M, López-Candales A, Ramani G, Rajagopalan N, Edelman K. Unusual echocardiographic features seen in a case of giant cell myocarditis. Can J Cardiol. 2008 Nov;24(11):855-6.

  21. Brown JR, Uber PA, Mehra MR . The progressive cardiorenal syndrome in heart failure: mechanisms and therapeutic insights. Curr Treat Options Cardiovasc Med. 2008 Aug;10(4):342-8.

  22. Mehra MR, Kobashigawa JA, Deng MC, Fang KC, Klingler TM, Lal PG, Rosenberg S, Uber PA, Starling RC, Murali S, Pauly DF, Dedrick R, Walker MG, Zeevi A, Eisen HJ; CARGO Investigators. Clinical implications and longitudinal alteration of peripheral blood transcriptional signals indicative of future cardiac allograft rejection.  J Heart Lung Transplant. 2008 Mar;27(3):297-301.

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Echocardiography

  1. Vesely MR, Li S, Kop WJ, Reese A, Marshall J, Shorofsky SR, Gottlieb SS, Mehra MR, Gottdiener JS. Test-retest reliability of assessment for intraventricular dyssynchrony by tissue Doppler imaging echocardiography. Am J Cardiol. 2008 Mar 1;101(5):645-50.

  2. Schwartz DJ, Kop WJ, Park MH, Vesely MR, Li S, Mehra MR, Gottdiener JS. Evidence for early right ventricular and septal mechanical activation (interventricular dyssynchrony) in pulmonary hypertension. Am J Cardiol. 2008 Nov 1;102(9):1273-7.

  3. Gammie JS, Krowsoski LS, Brown JM, Odonkor PN, Young CA, Santos MJ, Gottdiener JS, Griffith BP.  Aortic valve bypass surgery: midterm clinical outcomes in a high-risk aortic stenosis population.  Circulation. 2008 Sep 30;118(14):1460-6.

  4. Chami HA, Devereux RB, Gottdiener JS, Mehra R, Roman MJ, Benjamin EJ, Gottlieb DJ.  Left ventricular morphology and systolic function in sleep-disordered breathing: the Sleep Heart Health Study.  Circulation. 2008 May 20;117(20):2599-607.

  5. de Simone G, Gottdiener JS, Chinali M, Maurer MS.  Left ventricular mass predicts heart failure not related to previous myocardial infarction: the Cardiovascular Health Study.    Eur Heart J. 2008 Mar;29(6):741-7.

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Electrophysiology

  1. Stein PK, Barzilay JI, Chaves PH, Traber J, Domitrovich PP, Heckbert SR, Gottdiener JS. Higher levels of inflammation factors and greater insulin resistance are independently associated with higher heart rate and lower heart rate variability in normoglycemic older individuals: the Cardiovascular Health Study. J Am Geriatr Soc. 2008 Feb;56(2):315-21.

  2. Stein PK, Barzilay JI, Chaves PH, Mistretta SQ, Domitrovich PP, Gottdiener JS, Rich MW, Kleiger RE. Novel measures of heart rate variability predict cardiovascular mortality in older adults independent of traditional cardiovascular risk factors: the Cardiovascular Health Study (CHS).  J Cardiovasc Electrophysiol. 2008 Nov;19(11):1169-74.

  3. Stein PK, Barzilay JI, Chaves PH, Domitrovich PP, Gottdiener JS.  Heart rate variability and its changes over 5 years in older adults.  Age Ageing. 2009 Jan 15

  4. Haigney MC, Kop WJ, Alam S, Krantz DS, Karasik P, DelNegro AA, Gottdiener JS.QT variability during rest and exercise in patients with implantable cardioverter defibrillators and healthy controls. Ann Noninvasive Electrocardiol. 2009 Jan;14(1):40-9.

  5. Tian J, Smith MF, Chinnadurai P, Dilsizian V, Turgeman A, Abbo A, Gajera K, Xu C, Plotnick D, Peters R, Saba M, Shorofsky S, Dickfeld T. Clinical Application of PET/CT Fusion Imaging for Three-Dimensional Myocardial Scar and Left Ventricular Anatomy during Ventricular Tachycardia Ablation. J Cardiovasc Electrophysiol. 2008 Dec 15.

  6. Lieberman R, Havel WJ, Rashba E, DeGroot PJ, Stromberg K, Shorofsky SR. Acute defibrillation performance of a novel, non-transvenous shock pathway in adult ICD indicated patients. Heart Rhythm. 2008 Jan;5(1):28-34.

  7. Dickfeld T, Kocher C. The role of integrated PET-CT scar maps for guiding ventricular tachycardia ablations. Curr Cardiol Rep. 2008 Mar;10(2):149-57. Review

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Cardiovascular Science

  1. Duda MK, O'Shea KM, Tintinu A, Xu W, Khairallah RJ, Barrows BR, Chess DJ, Azimzadeh AM, Harris WS, Sharov VG, Sabbah HN, Stanley WC.   Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction.  Cardiovasc Res. 2009 Feb 1;81(2):319-27.

  2. Chess DJ, Xu W, Khairallah R, O'Shea KM, Kop WJ, Azimzadeh AM, Stanley WC.  The antioxidant tempol attenuates pressure overload-induced cardiac hypertrophy and contractile dysfunction in mice fed a high-fructose diet. Am J Physiol Heart Circ Physiol. 2008 Dec;295(6):H2223-30.

  3. Qanud K, Mamdani M, Pepe M, Khairallah RJ, Gravel J, Lei B, Gupte SA, Sharov VG, Sabbah HN, Stanley WC, Recchia FA. Reverse changes in cardiac substrate oxidation in dogs recovering from heart failure.  Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H2098-105.

  4. Rastogi S, Sharov VG, Mishra S, Gupta RC, Blackburn B, Belardinelli L, Stanley WC, Sabbah HN.  Ranolazine combined with enalapril or metoprolol prevents progressive LV dysfunction and remodeling in dogs with moderate heart failure. Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H2149-55.

  5. Zhou L, Huang H, McElfresh TA, Prosdocimo DA, Stanley WC. Impact of anaerobic glycolysis and oxidative substrate selection on contractile function and mechanical efficiency during moderate severity ischemia. Am J Physiol Heart Circ Physiol. 2008 Sep;295(3):H939-H945.

  6. Lei B, Chess DJ, Keung W, O'Shea KM, Lopaschuk GD, Stanley WC.  Transient activation of p38 MAP kinase and up-regulation of Pim-1 kinase in cardiac hypertrophy despite no activation of AMPK.  J Mol Cell Cardiol. 2008 Sep;45(3):404-10.

  7. Zungu M, Young ME, Stanley WC, Essop MF.  Expression of mitochondrial regulatory genes parallels respiratory capacity and contractile function in a rat model of hypoxia-induced right ventricular hypertrophy.  Mol Cell Biochem. 2008 Nov;318(1-2):175-81.

  8. Lu M, Zhou L, Stanley WC, Cabrera ME, Saidel GM, Yu X.    Role of the malate-aspartate shuttle on the metabolic response to myocardial ischemia.  J Theor Biol. 2008 Sep 21;254(2):466-75.

  9. Yuan CL, Sharma N, Gilge DA, Stanley WC, Li Y, Hatzoglou M, Previs SF. Preserved protein synthesis in the heart in response to acute fasting and chronic food restriction despite reductions in liver and skeletal muscle.  Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E216-22.

  10. Lockridge JB, Sailors ML, Durgan DJ, Egbejimi O, Jeong WJ, Bray MS, Stanley WC, Young ME. Bioinformatic profiling of the transcriptional response of adult rat cardiomyocytes to distinct fatty acids. J Lipid Res. 2008 Jul;49(7):1395-408.

  11. Yaniv Y, Stanley WC, Saidel GM, Cabrera ME, Landesberg A. The role of Ca2+ in coupling cardiac metabolism with regulation of contraction: in silico modeling. Ann N Y Acad Sci. 2008 Mar;1123:69-78.

  12. Glatz JF, Stanley WC.  Myocardial Metabolism-Therapeutic Aspects. Cardiovasc Drugs Ther. 2008 Mar 28.

  13. Chess DJ, Stanley WC. Role of diet and fuel overabundance in the development and progression of heart failure. Cardiovasc Res. 2008 Jul 15;79(2):269-78.

  14. Zhou L, Huang H, Yuan CL, Keung W, Lopaschuk GD, Stanley WC. Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation. Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H954-60.

  15. Duda MK, O'Shea KM, Lei B, Barrows BR, Azimzadeh AM, McElfresh TE, Hoit BD, Kop WJ, Stanley WC. Low-carbohydrate/high-fat diet attenuates pressure overload-induced ventricular remodeling and dysfunction. J Card Fail. 2008 May;14(4):327-35.

  16. Kardia SL, Kelly RJ, Keddache MA, Aronow BJ, Grabowski GA, Hahn HS, Case KL, Wagoner LE, Dorn GW 2nd, Liggett SB. Multiple interactions between the alpha 2C- and beta1-adrenergic receptors influence heart failure survival. BMC Med Genet. 2008 Oct 23;9:93.

  17. Sehnert AJ, Daniels SE, Elashoff M, Wingrove JA, Burrow CR, Horne B, Muhlestein JB, Donahue M, Liggett SB, Anderson JL, Kraus WE.  Lack of association between adrenergic receptor genotypes and survival in heart failure patients treated with carvedilol or metoprolol.  J Am Coll Cardiol. 2008 Aug 19;52(8):644-51.

  18. Swift SM, Gaume BR, Small KM, Aronow BJ, Liggett SB.  Differential coupling of Arg- and Gly389 polymorphic forms of the beta1-adrenergic receptor leads to pathogenic cardiac gene regulatory programs.  Physiol Genomics. 2008 Sep 17;35(1):123-31. Epub 2008 Jul 29. Erratum in: Physiol Genomics. 2008 Oct 8;35(2):198.

  19. Wang WC, Mihlbachler KA, Bleecker ER, Weiss ST, Liggett SB.  A polymorphism of G-protein coupled receptor kinase5 alters agonist-promoted desensitization of beta2-adrenergic receptors.  Pharmacogenet Genomics. 2008 Aug;18(8):729-32.

  20. Liggett SB, Cresci S, Kelly RJ, Syed FM, Matkovich SJ, Hahn HS, Diwan A, Martini JS, Sparks L, Parekh RR, Spertus JA, Koch WJ, Kardia SL, Dorn GW 2nd.  A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure.  Nat Med. 2008 May;14(5):510-7.

  21. Einstein R, Jordan H, Zhou W, Brenner M, Moses EG, Liggett SB.  Alternative splicing of the G protein-coupled receptor superfamily in human airway smooth muscle diversifies the complement of receptors. Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5230-5.

  22. Small KM, Mialet-Perez J, Liggett SB. Genetic variation within the beta1-adrenergic receptor gene results in haplotype-specific expression phenotypes. J Cardiovasc Pharmacol. 2008 Jan;51(1):106-10.

  23. Panebra A, Schwarb MR, Swift SM, Weiss ST, Bleecker ER, Hawkins GA, Liggett SB.  Variable-length poly-C tract polymorphisms of the beta2-adrenergic receptor 3'-UTR alter expression and agonist regulation.  Am J Physiol Lung Cell Mol Physiol. 2008 Feb;294(2):L190-5.

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Miscellaneous

  1. Kastor JA.  Reducing deficits, increasing surpluses in medical schools.  Acad Med. 2008 Nov;83(11):997-8.

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