Simian crease:

A simian crease is a single palmar crease as compared to two creases in a normal palm. Simian crease occurs in about 1 out of 30 normal people, but is also frequently associated with other conditions such as Down syndrome, Aarskog syndrome or fetal alcohol syndrome.
- Reviewed last on: 2/5/2008
- Chad Haldeman-Englert, MD, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA. Review provided by VeriMed Healthcare Network.