The Maryland Center for Multiple Sclerosis

Physicians and Staff

Walter Royal, III, M.D.

Dr. Royal is an Associate Professor of Neurology at the University of Maryland School of Medicine. He came to the Maryland Center of Multiple Sclerosis in January of 2005. Prior to this time, he was at Morehouse School of Medicine in Atlanta, GA where he served as an Associate Professor of Medicine (Neurology) and Anatomy and Neurobiology. He is familiar to the Baltimore area having served as the Director of the Johns Hopkins MS Center from 1998-2000.

Dr. Royal is the Research Associate Director for the VA Multiple Sclerosis Center, East and for the Maryland Center for Multiple Sclerosis. He is an active investigator in the Maryland Center for MS clinical trials program and also has a laboratory which is researching the mechanisms by which members of a family of nuclear receptors are able to modulate proinflammatory immune responses in MS. Among the members of this receptor family are those that bind vitamin A and vitamin D.

Dr. Royal will see patients in the Neurology Ambulatory Center on Tuesdays. Appointments may be made by calling the appointment desk at 410-328-5858.

Administrative Office Address:	Patient Appointment Address:
Maryland Center for MS 11 South Paca St., 4th floor Baltimore, MD 21201 Phone 410-328-5605 Fax 410-328-5425	Neurology Ambulatory Center 16 South Eutaw Street, 3rd floor Baltimore, MD 21201 Phone 410-328-5858 Fax 410-328-1149

Education and Training:
1973-1977	Harvard College Cambridge, Massachusetts A.B., Biochemistry
1977-1980	Dartmouth Medical School M.D. Hanover, New Hampshire
1980-1983	Residency in Internal Medicine Faulkner Hospital, Boston, Massachusetts
1983-1985	Post-doctoral Fellowship Neurovirology and neuroimmunology Johns Hopkins University, Baltimore, MD
1985-1988	Residency in Neurology The Johns Hopkins Hospital, Baltimore, MD
Previous Appointments
1988-1991	Instructor in Neurology Johns Hopkins University
1991-2000	Assistant Professor in Neurology Johns Hopkins University

Certifications
American Board of Internal Medicine (Certified 9/83) American Board of Psychiatry and Neurology (Certified 9/90

Current Appointments
2005-Present	Associate Professor of Neurology University of MD School of Medicine
2000-2005	Associate Professor of Medicine (Neurology and Anatomy and Neurobiology Morehouse School of Medicine

Selected publications and invited reviews (out of more than 40 published papers)

Royal III W. HIV-1 Related Neurologic Disease: Therapeutic Issues. Journal of NeuroVirology 2000; Suppl: S33-S37.
Geschwind MD, Slolasky RL, Royal III W, McArthur JC. The relative contributions of HAART and alpha-interferon for therapy of progressive multifocal leukoencephalopathy. Journal of NeuroVirology. 2001; 7:353-357.
Bilak MM, Coarse AM, Royal W , Becerra P, Cristofalo V, Francis MK, Kuncl RW. Pigment epithelium-derived factor (PEDF) is elevated in cerebrospinal fluid (CSF) of patients with amyotrophic lateral sclerosis (ALS). J Neurochem 2002; 81:178-184.
Royal III W , Khalsa JH, Francis H. Proceedings of a workshop on metabolic disorders in the pathogenesis of nervous system damage in HIV-infected drug users. JAIDS. 2002; 31:S27-S28.
Royal III W , Gartner S, Gadjewski CD. Retinol measurements and retinol receptor gene expression in patients with multiple sclerosis. Multiple Sclerosis. 2002; 8:452-458.
Royal III W, Dupont B, McGuire D, Chang L, Goodkin K, Ernst T, Post MJ, Fish D, Pailloux G, Poncelet H, Concha M, Apuzzo L, Singer, E. Topotecan in the treatment of AIDS-related progressive multifocal leukoencephalopathy. Journal of NeuroVirology. 2003;9: 411-419.
Royal III W, Vlahov D, Lyles C, Gajewski CD. Retinoids and drugs of abuse: Implication for Neurologic Disease Risk in HIV-1 Infection. Clinical Infectious Diseases. 2003; Suppl 5: S427-S432.
Retinoid-induced Immunomodulation: inhibition by morphine and implications for nervous system disease in HIV-1 infection. Proceedings from the NIDA-Sponsored Satellite Sessions in Association with the XIV International AIDS Conference, Barcelona, Spain (Satillite Sessions, XIV International AIDS Conference, Barcelona, Spain, July, 2002.) Bethesda, MD, National Institute on Drug Abuse, pp 56-59, 2003.
Mou L, Lankford-Turner P, Leander MV, Bissonnette RP, Donohoe RM, Royal W III . RXR-induced TNF-a Suppression is Reversed by Morphine in Phytohemagglutanin-activated U937 Cells. Journal of Neuroimmunology. 2004;147:99-105.
Khalsa JH and Royal III W . Do Drugs of Abuse Impact on HIV Disease? Journal of Neuroimmunology. 2004; 147:6-8.

This page was last updated on: August 29, 2007.

For more information about the Maryland Center for Multiple Sclerosis,
please call 410-328-5605.