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Scleroderma

Description

An in-depth report on the causes, diagnosis, treatment, and prevention of scleroderma.

Alternative Names

Systemic sclerosis

References

Tashkin DP, Elashoff R, Clements PJ, et al. Cyclophosphamide versus placebo in scleroderma lung disease. N Engl J Med . 2006; 354(25):2655-66

Barr WG, Oyama Y, Statkute L, et al. Autologous Non-Myeloablative Peripheral Blood Stem Cell Transplantation in Patients with Systemic Sclerosis. American College of Rheumatology Annual Meeting, 2006. Presentation 688.

National Institute of Arthritis, Musculoskeletal, and Skin Diseases. Scleroderma: Summaries of Research. November 2006. Last accessed on 1 December, 2006.

Casciola-Rosen L, Wigley F, and Rosen A. Scleroderma Autoantigens Are Uniquely Fragmented by Metal-catalyzed Oxidation Reactions: Implications for Pathogenesis. J. Exp. Med . 1997; 185 (January): 71-80. Last accessed on 27 November, 2006.

van Laar JM. Autologous Stem cell Transplantation International Scleroderma (ASTIS) trial: hope on the horizon for patients with severe systemic sclerosis. Ann Rheum Dis. 2005; 64(10): 1515.

van Laar JM. High-dose immunosuppressive therapy and autologous progenitor cell transplantation for systemic sclerosis. Best Pract Res Clin Haematol. 2 004; 17(2): 233-45.

Crofford LJ. Immunomodulatory therapy for SSc: will high-intensity immunosuppression with stem cell rescue improve outcome? Curr Rheumatol Rep. 2005; 7(2): 142-9.

Toledano C, Henegar C, Ilie D et al. Cardiopulmonary function before and after cyclophosphamide treatment in severe systemic sclerosis: comparison of monthly intravenous bolus and autologous haematopoietic stem cell transplantation. Rev Med Interne . 2005 Jun;26(6):444-52.

Pfizenmaier DH 2nd, Kavros SJ, Liedl DA, Cooper LT. Use of intermittent pneumatic compression for treatment of upper extremity vascular ulcers. Angiology. 2005 Jul-Aug;56(4):417-22.

Shoenfeld Y, Katz U. IVIg therapy in autoimmunity and related disorders: our experience with a large cohort of patients. Autoimmunity . 2005 Mar;38(2):123-37.

• Review Date: 12/14/2006
• Reviewed By: Harvey Simon, MD, Associate Professor of Medicine, Harvard Medical School; Physician, Massachusetts General Hospital

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