Measles; Rubella; Tetanus; Vaccinations; Whooping cough
Hib Vaccine Shortage
In December 2007 the Merck company ceased production of its Haemophilus influenza type b (Hib) vaccine due to possible contamination. Merck does not expect to continue producing this vaccine until mid-2009. While there are 2 other Hib vaccines on the market, they cannot fill up the entire demand for the full vaccine schedule. As a result, the Centers for Disease Control and Prevention (CDC) and the American Academy of Pediatrics are recommending that the booster dose of Hib (normally given to children between 12 and 15 months of age) be deferred, except for children at high risk. It is imperative, however, that babies receive the initial Hib series at ages 2, 4, and 6 months.
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Centers for Disease Control and Prevention. Recommended Immunization Schedule for Ages 0 - 6 Years, United States, 2009.
Centers for Disease Control and Prevention. Recommended Immunization Schedule for Ages 7 - 18 Years, United States, 2009.
Centers for Disease Control and Prevention. Recommended Immunization Schedule for Adults, United States, 2009. Available online.
Centers for Disease Control and Prevention. Revised Recommendations of the Advisory Committee on Immunization Practices to Vaccinate All Persons Aged 11 - 18 Years with Meningococcal Conjugate Vaccine. Morbidity and Mortality Weekly Report. 2007:56(31);794-795.
Centers for Disease Control and Prevention. Notice to Readers: Recommendation from the Advisory Committee on Immunization Practices (ACIP) for Use of Quadrivalent Meningococcal Conjugate Vaccine (MCV4) in Children Aged 2 - 10 Years at Increased Risk for Invasive Meningococcal Disease. Morbidity and Mortality Weekly Report. 2007;56(48);1265-1266.
Centers for Disease Control and Prevention. Prevention of influenza: Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2008. Morbidity and Mortality Weekly Report. 2008:57(No. RR-7).
Centers for Disease Control and Prevention. Update on Hib Vaccine Shortage. October 22, 2008. Available online.
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GlaxoSmithKline. Boostrix Prescribing Information. December, 2008.
Grijalva CG, Nuorti JP, Arbogast PG, Martin SW, Edwards KM, Griffin MR. Decline in pneumonia admissions after routine childhood immunisation with pneumococcal conjugate vaccine in the USA: a time-series analysis. Lancet. April 7, 2007;369:1179-1186.
Poehling KA, Szilagyi PG, Crijalva CG, Martin SW, LaFleur B, Mitchel E, et al. Reduction of frequent otitis media and pressure-equalizing tube insertions in children after introduction of pneumococcal conjugate vaccine. Pediatrics. April 4, 2007;119:707-715.
US Food and Drug Administration. FDA Approves Expanded Uses for Gardasil to Include Preventing Certain Vulvar and Vaginal Cancers. September 12, 2008.
US Food and Drug Administration. FDA Approves New Vaccine to Prevent Gastroenteritis Caused by Rotavirus. April 3, 2008.
US Food and Drug Administration. Zostavax Questions and Answers. Available online. Last Accessed 3/12/2009.
World Health Organization. Immunization surveillance, assessment and monitoring -- United States of America (the) reported cases. Last Updated: December 18, 2008. Available online.
Zuckerman JN. Protective efficacy, immunotherapeutic potential, and safety of hepatitis B vaccines. J Med Virol. 2006 Feb;78(2):169-77.
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