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Premenstrual syndrome - Highlights

Description

An in-depth report on the causes, diagnosis, treatment, and prevention of premenstrual syndrome (PMS).

Alternative Names

PMS

Highlights:

Premenstrual Syndrome Symptoms

Premenstrual syndrome (PMS) can produce physical and emotional or behavioral symptoms.

Physical symptoms of PMS may include:

  • Breast engorgement and tenderness
  • Abdominal bloating
  • Constipation or diarrhea
  • Headache and migraine
  • Swelling of the hands or feet
  • Weight gain
  • Clumsiness
  • Nausea and vomiting
  • Muscle and joint aches or pains

Emotional and behavioral symptoms of PMS may include:

  • Depression (severe depression before menstruation, called premenstrual dysphoric disorder, occurs in about 5% of women with PMS)
  • Anxiety and panic attacks
  • Insomnia
  • Change in sexual interest and desire
  • Irritability
  • Hostility and outbursts of anger
  • Increased appetite often with specific food cravings (especially salt and sugar)
  • Mood swings
  • Inability to concentrate
  • Lethargy and fatigue

Premenstrual Dysphoric Disorder

Premenstrual dysphoric disorder (PMDD) is a specific psychiatric condition marked by severe depression, irritability, and tension before menstruation. For a doctor to confirm a diagnosis of PMDD, the patient must have symptoms during the last week of the premenstrual phase and that resolve within a few days after menstruation starts.

Five or more of the following symptoms must occur:

  • Feeling of sadness or hopelessness, possible suicidal thoughts
  • Feelings of tension or anxiety (panic attacks, in fact, may be much more common in patients with PMDD than in the general population)
  • Mood swings marked by periods of teariness
  • Persistent irritability or anger that affects other people
  • Disinterest in daily activities and relationships
  • Trouble concentrating
  • Fatigue or low energy
  • Food cravings or bingeing
  • Sleep disturbances
  • Feeling out of control
  • Physical symptoms, such as bloating, breast tenderness, headaches, and joint or muscle pain

Resources

References

Braverman PK. Premenstrual syndrome and premenstrual dysphoric disorder. J Pediatr Adolesc Gynecol. 2007 Feb;20(1):3-12.

Brown J, O' Brien PM, Marjoribanks J, Wyatt K. Selective serotonin reuptake inhibitors for premenstrual syndrome. Cochrane Database Syst Rev. 2009 Apr 15;(2):CD001396.

Jarvis CI, Lynch AM, Morin AK. Management strategies for premenstrual syndrome/premenstrual dysphoric disorder. Ann Pharmacother. 2008 Jul;42(7):967-78. Epub 2008 Jun 17

Kwan I and Onwude JL. Premenstrual syndrome. BMJ Clinical Evidence. Web publication date: 01 May 2007.

Lentz GM. Primary and secondary dysmenorrheal, premenstrual syndrome, and premenstrual dysphoric disorder. Etiology, diagnosis, management. In: Katz VL, Lobo RA, Lentz G, Gershenson D, eds. Comprehensive Gynecology. 5th ed. St. Louis, MO: Mosby; 2007:chap 36.

Lopez LM, Kaptein AA, Helmerhorst FM. Oral contraceptives containing drospirenone for premenstrual syndrome. Cochrane Database Syst Rev. 2009 Apr 15;(2):CD006586.

Yonkers KA, O'Brien PM, Eriksson E. Premenstrual syndrome. Lancet. 2008 Apr 5;371(9619):1200-10.

  • Reviewed last on: 8/4/2009
  • Harvey Simon, MD, Editor-in-Chief, Associate Professor of Medicine, Harvard Medical School; Physician, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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