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Hodgkin's disease - Symptoms

Description

An in-depth report on the causes, diagnosis, treatment, and prevention of Hodgkin's disease.

Alternative Names

Lymphoma - Hodgkin's; Hodgkin's lymphoma; Hodgkins disease; HD

Symptoms:

Symptoms of Hodgkinâ ' s disease may include:

  • Swollen (but painless) lymph nodes in the neck, armpits, or groin
  • Pain in lymph nodes after drinking alcohol
  • Itching throughout body (pruritis)
  • Persistent fatigue
  • Coughing, difficulty breathing, or chest pain may indicate that swollen lymph nodes in the chest are pressing on the windpipe
  • Unexplained weight loss of more than 10% in previous 6 months
  • Persistent fever
  • Drenching night sweats

The last three symptoms (weight loss, fever, and night sweats) are classified as “B symptoms.” B symptoms may be used in staging Hodgkinâ ' s disease and can indicate that more aggressive treatment will be required.

Sometimes patients with Hodgkinâ ' s disease do not experience any symptoms, or symptoms may not appear until the cancer is very advanced. Enlarged lymph nodes can also be caused by many noncancerous conditions, such as infections.

Resources

References

American Cancer Society. Cancer Facts and Figures 2008. Atlanta, Ga: American Cancer Society, 2008.

Brenner H, Gondos A, Pulte D. Ongoing improvement in long-term survival of patients with Hodgkin disease at all ages and recent catch-up of older patients. Blood. 2008;111 (6): 2977-83.

Fermé C, Eghbali H, Meerwaldt JH, et al. Chemotherapy plus involved-field radiation in early-stage Hodgkin's disease. N Engl J Med. 2007 Nov 8;357(19):1916-27.

Horning SJ. Hodgkin’s lymphoma. In: Abeloff MD, Armitage JO, Niederhuber JE, Kastan MB, McKena WG, eds. Clinical Oncology. 4th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 111.

Juweid ME, Stroobants S, Hoekstra OS, et al. Use of positron emission tomography for response assessment of lymphoma: consensus of the Imaging Subcommittee of International Harmonization Project in Lymphoma. J Clin Oncol. 2007 Feb 10;25(5):571-8. Epub 2007 Jan 22.

National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Hodgkin Disease / Lymphoma. V.2.2009.

Oeffinger KC, Ford JS, Moskowitz CS, Diller LR, Hudson MM, Chou JF, et al. Breast cancer surveillance practices among women previously treated with chest radiation for a childhood cancer. JAMA. 2009 Jan 28;301(4):404-14.

  • Reviewed last on: 3/5/2009
  • Harvey Simon, MD, Editor-in-Chief, Associate Professor of Medicine, Harvard Medical School; Physician, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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