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High blood pressure - Diagnosis

Description

An in-depth report on the causes, diagnosis, treatment, and prevention of high blood pressure.

Alternative Names

Hypertension

Diagnosis:

Most physical exams include a blood pressure measurement. Patients should not smoke, exercise, or drink caffeinated beverages within 30 minutes before their blood pressure measurement.

Measuring Blood Pressure

  • The standard instrument used to measure blood pressure is called a sphygmomanometer. Measurements are given as units of mercury, which has filled the central column in standard sphygmomanometers for years. (Modern devices are designed to prevent mercury spillage.)
  • An inflatable cuff with a meter attached is placed around the patient's arm over the artery while the patient is seated, their back is supported, and the arm being used is around the level of the heart. The inflated cuff briefly interrupts the flow of blood in the artery, which then resumes as the cuff is slowly deflated.
  • The person taking the blood pressure listens through a stethoscope.
  • The first pumping sound your health care provider hears is recorded as the systolic pressure, and the last sound is the diastolic pressure.
  • If a first blood pressure reading is above normal, the health professional may take two or more measurements separated by 2 minutes with the patient sitting or lying down. Another measurement may be taken after the patient has been standing for 2 minutes. If the measurements are still elevated, your health care provider should take blood pressure readings from both arms.
To measure blood pressure, your doctor uses an instrument called a "sphygmomanometer," more often referred to as a blood pressure cuff. The cuff is wrapped around your upper arm and inflated to stop the flow of blood in your artery. As the cuff is slowly deflated, your doctor uses a stethoscope to listen to the blood pumping through the artery. These pumping sounds register on a gauge attached to the cuff. The first pumping sound your doctor hears is recorded as the systolic pressure, and the last sound is the diastolic pressure.
Blood pressure check

Although this test has been used for more than 90 years, it is not completely accurate or sensitive. The following factors can cause a falsely low pressure reading:

  • An arm cuff that is too wide
  • Dehydration

Falsely high pressure can result from:

  • An arm cuff that is too small
  • Stress
  • Recently consuming foods or beverages (such as coffee) that raise blood pressure
  • Recent tobacco exposure
  • Recent exercise

Office blood pressure readings taken by a doctor are more likely to be higher than readings measured at home. This can be caused by "white coat hypertension," which is blood pressure that is only elevated during a doctor's office visit. It is defined as a daytime blood pressure away from the doctor's office of less than 135/85 mg Hg and no evidence of complications of blood pressure elsewhere in the body. Patients with white-coat hypertension may require additional blood pressure readings.

Ambulatory Monitoring

Doctors may ask some patients to use special ambulatory monitoring device for a 24-hour period. The device checks blood pressure about every 15 - 30 minutes during the day and night and provides a read-out of blood pressure measurements for the doctor. Ambulatory monitoring may be used for patients who have borderline high blood pressure or for those who have had difficulty keeping their blood pressure under control. It can also help distinguish between true and white-coat hypertension. Ambulatory monitoring can also be helpful for diagnosing children with suspected high blood pressure.

Home Monitoring

The American Heart Association (AHA) recommends that all patients with high blood pressure monitor their blood pressure at home on a regular basis. In addition to other benefits, home monitoring can help show if blood pressure medications are working.

The AHA recommends:

  • Purchase a blood pressure monitor with cuffs that fit on the upper arm. Wrist monitors are not recommended. Make sure that the cuff is the right size (one size does not fit all).
  • Ask your doctor to show you the proper way to use the monitor. Your arm should be supported, with the upper arm at heart level and feet on floor (back supported, legs uncrossed).
  • Take two or three readings at a sitting, 1 minute apart, while resting in a seated position. It is important to take the readings at the same time each day, such as morning and night. Your doctor may suggest what specific times readings should be taken.
  • The target goal of a reading is under 135/85 mm Hg or less than 130/80 mm Hg in high-risk patients.

Blood Pressure Variations at Home. In general, everyone's blood pressure varies in the same way throughout a given day. In monitoring at home, it is important to note these changes:

  • Blood pressure is usually highest from morning to mid-afternoon.
  • It normally dips to its lowest level during sleep. Some people (particularly postmenopausal women) have a condition called nondipper hypertension, in which blood pressure does not fall at night.

Stroke
Click the icon to see an image of stroke.
  • Upon waking, blood pressure in most people typically increases suddenly. In people with severe high blood pressure, this is the highest risk period for heart attack and stroke.

Acute MI
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Monitoring blood pressure
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Physical Examination for Complications of Hypertension

If blood pressure is elevated, the doctor will check the patient's pulse rate, examine the back of the eye, examine the neck for distended veins or an enlarged thyroid gland, check the heart for enlargement and murmurs, and examine the abdomen and check the leg pulses.


Thyroid gland
Click the icon to see an image of the thyroid gland.

Medical History

If hypertension is suspected, the doctor should obtain the following information:

  • A family and personal medical history, especially incidence of high blood pressure, stroke, heart problems, kidney disease, or diabetes.
  • Risk factors for heart disease and stroke, including tobacco use, salt intake, obesity, physical inactivity, and unhealthy cholesterol levels.
  • Any medications being taken.
  • Any symptom that might indicate so-called secondary hypertension (that is, caused by another disorder). Such symptoms include headache, heart palpitations, excessive sweating, muscle cramps or weakness, or excessive urination.
  • Any emotional or environmental factors that could affect blood pressure.

Laboratory and Other Tests

If a physical examination indicates hypertension, additional tests may help determine whether it is secondary hypertension caused by another medical disorder) and whether organ damage is present.

Blood Tests and Urinalysis. These tests are performed to check for a number of factors, including potassium levels, cholesterol, blood sugar (to screen for diabetes), infection, kidney function, and other possible problems. Measuring blood levels of the protein creatinine, for example, is important for all hypertensive patients in order to determine kidney damage.

Tests to Evaluate the Heart. These tests include:

  • An electrocardiogram (ECG) is performed on most patients in the doctor's office.

ECG
Click the icon to see an image of an electrocardiogram.
  • An exercise stress test may be needed for patients who also have symptoms of coronary artery disease.
  • An echocardiogram is needed when it would help the doctor decide whether to start treatment. Most of the time this test is not necessary for patients who have only hypertension and no other symptoms.

High blood pressure tests
Click the icon to see an image of blood pressure tests.

Tests To Evaluate the Kidneys. These tests include:

  • A Doppler or duplex test may be performed to see whether one of the arteries supplying blood to the kidney is narrowed, a condition called renal artery stenosis.
  • An ultrasound may also be performed to examine the kidneys.

Resources

References

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AHA; ACC; National Heart, Lung, and Blood Institute, Smith SC Jr, Allen J, Blair SN, Bonow RO, Brass LM, Fonarow GC, et al. AHA/ACC guidelines for secondary prevention for patients with coronary and other atherosclerotic vascular disease: 2006 update endorsed by the National Heart, Lung, and Blood Institute. J Am Coll Cardiol. 2006 May 16;47(10):2130-9.

Barzilay JI, Davis BR, Cutler JA, Pressel SL, Whelton PK, Basile J, et al. Fasting glucose levels and incident diabetes mellitus in older nondiabetic adults randomized to receive 3 different classes of antihypertensive treatment: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). Arch Intern Med. 2006 Nov 13;166(20):2191-201.

Bellamy L, Casas JP, Hingorani AD, Williams DJ. Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BMJ. 2007 Nov 10;335(7627):974. Epub 2007 Nov 1.

Beulens JW, Rimm EB, Ascherio A, Spiegelman D, Hendriks HF, Mukamal KJ. Alcohol consumption and risk for coronary heart disease among men with hypertension. Ann Intern Med. 2007 Jan 2;146(1):10-9.

Blood Pressure Lowering Treatment Trialists' Collaboration, Turnbull F, Neal B, Ninomiya T, Algert C, Arima H, et al Effects of different regimens to lower blood pressure on major cardiovascular events in older and younger adults: meta-analysis of randomised trials. BMJ. 2008 May 17;336(7653):1121-3. Epub 2008 May 14.

Calhoun DA, Jones D, Textor S, Goff DC, Murphy TP, Toto RD, et al. Resistant hypertension: diagnosis, evaluation, and treatment: a scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. Circulation. 2008 Jun 24;117(25):e510-26.

Connolly HM, Oh JK. Echocardiography. In: Libby P, Bonow RO, Mann DL, Zipes DP, eds. Libby: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Saunders; 2007:chap 14.

Cook NR, Obarzanek E, Cutler JA, Buring JE, Rexrode KM, Kumanyika SK, et al. Joint effects of sodium and potassium intake on subsequent cardiovascular disease: the Trials of Hypertension Prevention follow-up study. Arch Intern Med. 2009 Jan 12;169(1):32-40.

Din-Dzietham R, Liu Y, Bielo MV, Shamsa F. High blood pressure trends in children and adolescents in national surveys, 1963 to 2002. Circulation. 2007 Sep 25;116(13):1488-96. Epub 2007 Sep 10.

Fagard RH, Cornelissen VA. Incidence of cardiovascular events in white-coat, masked and sustained hypertension versus true normotension: a meta-analysis. J Hypertens. 2007 Nov;25(11):2193-8.

Gami AS and Somers VK. Sleep apnea and cardiovascular disease. In: Libby P, Bonow RO, Mann DL, Zipes DP, eds. Libby: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Saunders; 2007:chap 74.

Hansen ML, Gunn PW, Kaelber DC. Underdiagnosis of hypertension in children and adolescents. JAMA. 2007 Aug 22;298(8):874-9.

Kaplan NM. Systemic hypertension: therapy. In: Libby P, Bonow RO, Mann DL, Zipes DP, eds. Libby: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Saunders; 2007:chap 41.

Magnussen EB, Vatten LJ, Lund-Nilsen TI, Salvesen KA, Davey Smith G, Romundstad PR. Prepregnancy cardiovascular risk factors as predictors of pre-eclampsia: population based cohort study. BMJ. 2007 Nov 10;335(7627):978. Epub 2007 Nov 1.

Matchar DB, McCrory DC, Orlando LA, Patel MR, Patel UD, Patwardhan MB, et al. Systematic review: comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers for treating essential hypertension. Ann Intern Med. 2008 Jan 1;148(1):16-29. Epub 2007 Nov 5.

Pickering TG, Miller NH, Ogedegbe G, Krakoff LR, Artinian NT, Goff D; et al. Call to action on use and reimbursement for home blood pressure monitoring: a joint scientific statement from the American Heart Association, American Society Of Hypertension, and Preventive Cardiovascular Nurses Association. Hypertension. 2008 Jul;52(1):10-29. Epub 2008 May 22.

Urbina E, Alpert B, Flynn J, Hayman L, Harshfield GA, Jacobson M, et al. Ambulatory blood pressure monitoring in children and adolescents: recommendations for standard assessment: a scientific statement from the American Heart Association Atherosclerosis, Hypertension, and Obesity in Youth Committee of the council on cardiovascular disease in the young and the council for high blood pressure research. Hypertension. 2008 Sep;52(3):433-51. Epub 2008 Aug 4.

U.S. Preventive Services Task Force. Screening for type 2 diabetes mellitus in adults: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2008 Jun 3;148(11):846-54.

Victor RG and Kaplan NM. Systemic hypertension: mechanisms and diagnosis. In: Libby P, Bonow RO, Mann DL, Zipes DP, eds. Libby: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Saunders; 2007:chap 40.

Wolff T, Miller T. Evidence for the reaffirmation of the U.S. Preventive Services Task Force recommendation on screening for high blood pressure. Ann Intern Med. 2007 Dec 4;147(11):787-91.

  • Reviewed last on: 5/5/2009
  • Harvey Simon, MD, Associate Professor of Medicine, Harvard Medical School; Physician, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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