Current Neurosurgery Research Grants

Current Clinical and Non-Clinical Research Grants

University of Maryland's Bizhan Aarabi

Bizhan Aarabi, M.D.

Principal Investigator
NACTN: North American clinical trials network for treatment of spinal cord injury
Sponsor: Christopher and Dana Reeve Foundation
Date: 2004 - present

Principal Investigator
RISCIS: Multicenter, randomized, placebo-controlled, double-blind trial of efficacy and safety of Riluzole in acute spinal cord injury started within 12 hours of injury
Sponsors: AOSpine International, Christopher and Dana Reeve Foundation, and Rick Hansen Institute
Date: 2013 – present


University of Maryland's E Francois Aldrich

E. Francois Aldrich, M.D.

Principal Investigator
CLEAR III: Clot Lysis – Evaluating accelerated resolution of intraventricular hemorrhage, phase III
Sponsor: National Institutes of Health
Date: 2004 - present

Principal Investigator
Edge: EG-1962 and nimodipine vs. placebo in aneurysm
Sponsor: Edge Therapeutics, Inc.
Date: 2013 – present

Principal Investigator
DEF: Deferoxamine mesylate in intracerebral hemorrhage, a phase II prospective, multi-center, double-blind, randomized, placebo-controlled, phase II clinical trial
Sponsor: National Institutes of Health, NINDS
Date: 2013 – present

Principal Investigator
MISTIE III: Minimally invasive surgery plus rt-PA for intracranial hemorrhage evacuation
Sponsor: National Institutes of Health
Date: 2005 - present


University of Maryland's Howard Eisenberg

Howard M. Eisenberg, M.D.

Principal Investigator for the Clinical Site
SHINE: Stroke hyperglycemia insulin network effort (SHINE) trial protocol
Sponsor: National Institutes of Health, NINDS
Date: 2013 – present

Principal Investigator
Tremor: ExAblate MRI for essential tremor
Sponsor: InSightec
Date: Pending


Vladimir Gerzanich

Vladimir Gerzanich, M.D., Ph.D.

Principal Investigator
Role of TRP channels in secondary injury after brain edema
Sponsor: National Institutes of Health, NINDS
Date: 2011 - present

Principal Investigator
TRPM4 channel in spinal cord injury
Sponsor: National Institutes of Health, NINDS
Date: 2008 - present

Co-Principal Investigator
Sulfonylurea receptor 1 (SUR1) – A novel therapeutic target in ischemic stroke
Sponsor: National Institutes of Health, NHLBI
Date: 2006 – present


University of Maryland's Charles Sansur

Charles A. Sansur, M.D., M.H.Sc.

Co-Principal Investigator
RISCIS: Multicenter, randomized, placebo-controlled, double-blind trial of efficacy and safety of Riluzole in acute spinal cord injury started within 12 hours of injury
Sponsors: AOSpine International, Christopher and Dana Reeve Foundation, and Rick Hansen Institute
Date: 2013 – present



University of Maryland's J Marc Simard

J. Marc Simard, M.D., Ph.D.

Principal Investigator
Pathological role of the SUR1-regulated NC (Ca-ATP) channel in cortex after subarachnoid hemorrhage
Sponsor: National Institutes of Health
Date: 2009 – present

Principal Investigator
Spinal cord injury, progressive hemorrhagic necrosis and the NC (Ca-ATP) channel
Sponsor: National Institutes of Health
Date: 2009 – present

Principal Investigator
Sulfonylurea receptor 1 (SUR1) – A novel therapeutic target in ischemic stroke
Sponsor: National Institutes of Health
Date: 2005 – present

Partnering Principal Investigator
MINIR-II: Minimally invasive neurosurgical intracranial robot
Sponsor: National Institutes of Health, NIBIB
Date: 2012 - present

Principal Investigator
Role of SUR1 in secondary hemorrhage following traumatic brain injury
Sponsor: Department of Veterans Affairs
Date: 2010 – present

Principal Investigator
Brain injury due to transcranial versus transthoracic blast exposure
Sponsor: Department of Veterans Affairs
Date: 2013 – present

Co-Principal Investigator
Role of TRP channels in secondary injury after brain trauma
Sponsor: National Institutes of Health, NINDS
Date: 2011 - present

Co-Principal Investigator
TRPM4 channel in spinal cord injury
Sponsor: National Institutes of Health, NINDS
Date: 2008 - present

Co-Principal Investigator
CLEAR III: Clot Lysis – Evaluating accelerated resolution of intraventricular hemorrhage, phase III
Sponsor: National Institutes of Health
Date: 2004 - present

Co-Principal Investigator
MISTIE III: Minimally invasive surgery plus rt-PA for intracranial hemorrhage evacuation
Sponsor: National Institutes of Health
Date: 2005 - present