Stephen Liggett, M.D.
Professor of Medicine and Physiology
Director, Cardiopulmonary Genomics
Medicine: Pulmonary and Critical Care Medicine
Special Interests: Asthma
Medical Degree: University of Miami (1982)
Residency: Barnes Hospital and Washington University
School of Medicine, St. Louis, MO (1982-1985)
Fellowship: Pulmonary Diseases and Critical Care Medicine, Washington University School of Medicine, St. Louis, MO Laboratory of Philip Cryer (1985-1988);
Research Fellow, laboratory of Robert J. Lefkowitz, Howard Hughes Medical Institute and Duke University Medical Center, Durham, NC (1988-1990)
Certification: Internal Medicine; Pulmonary Diseases; Critical Care Medicine (eligible)
Research Interest: Doctor Liggett is an internationally recognized leader in the field of G-protein coupled receptor biology, congestive heart failure, and asthma. He has not only made seminal discoveries in this field, but he has also recognized as one of the forces that has moved the field forward. He uses a bedside-to-bench-to-bedside approach in which polymorphisms (variations in sequence) in genes for adrenergic receptors contributes to pathogenesis and response to therapy in asthma and heart failure. Human genes encoding various polymorphisms are studied functionally in cell culture and transgenic mouse models and the findings are returned to the clinical arena to analyze the influence of these polymorphisms on disease pathogenesis and therapeutic responses in humans.
1-800-373-4111 (physicians only)
1-800-492-5538 (patients only)
1-410-328-8919 (news media only)