Division of Pulmonary and Critical Care

Publications

A, Keay TJ, Roy SC, Silverman HJ, Tasker DJ, Timmel D, Schwartz J, Wolfsthal SD. Development of Required Postgraduate Palliative Care Training for Internal Medicine Residents and Medical Oncology Fellows. J Cancer Edu. 2004; 19:81-87.

A. E. Medvedev, A. Lentschat, D. B. Kuhns, J. C. G. Blanco, C. Salkoswski, S. Zhang, M. Arditi, J. I. Gallin, and S. N. Vogel. Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and Interleukin-1 in a patient with recurrent bacterial infections. J. Exp. Med. 2003; 198: 521-531.

Afulukwe IF, Cohen RI, Zeballos GA, Iqbal M, Scharf SM. Selective NOS inhibition restores myocardial contractility in endotoxemic rats; however myocardial NO content does not correlate with myocardial dysfunction. Am J Resp Crit Care Med 2000; 162: 21 - 26.

Alexander, M., C. Forster, K. Sugimoto, H. B. Clark, S. N. Vogel, M. E. Ross, and C. Iadecola. IRF-1 immunoreactivity in neurons and inflammatory cells following ischemic stroke in rodents and human. Acta Neuropathologica 2002; 105: 420-424

Amelung PJ, Scott AF, Bleecker ER. Genetics of Bronchial Hyperresponsiveness. In: Lung Biology in Health and Diseases, C Lenfant, Exec. Ed. Genetics of Asthma, S Legett, DA Meyers, Eds, Marcel Dekker, Inc., New York 1996: pp. 525-545.

Armant, M. and M. J. Fenton. Mammalian Toll-like Receptors: a Family of Pattern Recognition Receptors. Genome Biology 2002; 3: 3011.1-3011.6,.

Atamas SP, Luzina IG, Choi J, Tsymbalyuk N, Carbonetti NH, Singh IS, Trojanowska M, Jimenez SA, White B. (2003) Pulmonary and Activation-Regulated Chemokine Stimulates Collagen Production in Lung Fibroblasts. Am J Respir Cell Mol Biol. 2003; 29:743-9

Bannerman DD and Goldblum SE. Direct Effects of Endotoxin on the Endothelium: Barrier Function and Injury. Lab Invest 1999, 79:1181-1199.

Bannerman DD and Goldblum SE. Mechanisms of bacterial lipopolysaccharide-induced endothelial apoptosis. Am J Physiol 2003, 284:L899-L914.

Basu, S. and M. J. Fenton. Toll-like Receptors: Function and Roles in Lung Disease. Amer. J. Physiol. Lung Cell Mol. Physiol. 2004; 286: L887-92.

Becker, S., M. J. Fenton, and J. M. Soukup. Involvement of Microbial Components and Toll-like Receptors 2 and 4 in Cytokine Responses to Air Pollution Particles. Am. J. Respir. Cell Mol. Biol. 2002; 27: 611-8.

Bhat N. ,, P.-Y. Perera, J.M. Carboni, J. Blanco, D.T. Golenbock, T.N. Mayadas, and S.N. Vogel. Use of a photoactivatable Taxol analog to identify unique cellular targets: Identification of murine CD18 as a major Taxol-binding protein and a role for Mac-1 in Taxol-induced gene expression. J. Immunol1999; 162: 7335-7342.

Blanco J.C.G. C. Contursi, C.A. Salkowski, D. L. DeWitt, K. Ozato, and S.N. Vogel. Interferon regulatory factor (IRF)-1 and IRF-2 regulate interferon-?-dependent cyclooxygenase II (Cox-2) expression. J. Exp. Med. 2000;191: 2131-2144.

Bolcato-Bellemin, A.L., M. G. Mattei, M. J. Fenton, and S. Amar. Molecular cloning and characterization of mouse LITAF cDNA: role in the regulation of tumor necrosis factor-alpha (TNF-a) gene expression. J. Endotoxin Res. 2004; 10: 15-23.

Bradford, M., A. J. Schroeder, H. C. Morse III, S. N. Vogel, and J. S. Cowdery. CPG DNA induced IL-12 p40 gene activation is independent of STAT1 activation or production of interferon consensus sequence binding protein (ICSBP). J. Biomedical Science 2002; 9:688-696.

Castro M, Dozor A, Fish J, Irvin C, Scharf SM, Scheipeter ME, Holbrook J, Tonascia J, Wise R (Writing Committee for the American Lung Association Asthma Clinical Research Centers). Safety of inactivated influenza vaccine in children and adults with asthma. New Eng J Med 2001; 345: 1529 - 1536.

Chandrasekar B, Melby PC, Sarau HM, Raveendran M, Perla RP, Marelli-Berg F, Dulin NO, Singh IS. Chemokine-Cytokine crosstalk. The ELR+ CXC chemokine LIX (CXCL5) amplifies a proinflammatory cytokine response via a PI3 kinase-NF-kappa B pathway. J. Biol. Chem. 2003; 278: 4675-4686

Chen L, Chen CX, Gan XT, Beier N, Scholz W, Karmazyn M. Inhibition and reversal of myocardial infarction-induced hypertrophy and heart failure by NHE-1 inhibition. Am J Physiol Heart Circ Physiol. 2004;286(1):H381-7.

Chen L, Gan XT, Haist JV, Feng Q, Lu X, Chakrabarti S, Karmazyn M. Attenuation of compensatory right ventricular hypertrophy and heart failure following monocrotaline-induced pulmonary vascular injury by the Na+-H+ exchange inhibitor cariporide. J Pharmacol Exp Ther. 2001;298(2):469-76.

Chen L, Scharf SM. Effects of aortic nerve on hemodynamic response to obstructive apnea in sedated pigs. J Appl Physiol 2000; 89: 1455 - 1461.

Chen L, Scharf SM. Hemodynamic effects of obstructive apneas in sedated pigs with congestive heart failure. J Appl Physiol 2000; 88: 1051 - 1060.

Chen L, Sica AL, Scharf SM. Mechanisms of acute cardiovascular response to periodic apneas in sedated pigs. J Appl Physiol 1999; 86: 1236 - 1246.

Chen, Y., J. M. Hallenbeck, D. Bol, K. Thomas, and S. N. Vogel. Overexpression of MCP-1 in the brain exacerbates ischemic brain injury and is associated with recruitment of monocytic cells. J. Cerebral Blood Flow and Metabolism (in press, 2003).

Cohen RI, Hassell A-M, Marzouk K, Marini C, Liu S-F, Scharf SM. Renal effects of nitric oxide in endotoxemia. Am J Resp and Crit Care Med. 2001; 164: 1890 - 1895.

Cohen RI, Marzouk K, Berkoski P, ODonnell CP, Polotsky VP, Scharf SM. Body composition and resting energy expenditure in clinically stable, non-weight losing patients with severe emphysema. Chest 2003; 124:1365 1372.

Cohen RI, Shapir Y, Davis A, Loona R, Scharf SM. Comparison between selective, non-selective nitric oxide synthase inhibition and phenylephrine in normal and endotoxic swine. Crit Care Med 2000, 28: 3257 - 3267.

Controlled Trials Evaluating Interventional Strategies: An Ethical Assessment. Crit Care Med. 2004; 32:852-857.

Core Panel Member, American Thoracic Society/European Respiratory Society International Multidisciplinary consensus Classification of the Idiopathic Interstitial Pneumonias Am J Respir Crit Care Med 2002;165:277-304.

Cowan MJ, Yao XL, Pawliczak R, Huang XL, Logun C, Madara P, Alsaaty S, Wu T, Shelhamer JH. The role of TFIID, the initiator element and a novel 5 TFIID binding site in the transcriptional control of the TATA-less human cytosolic phospholipase A2-a promoter. Biochim Biophys Acta 2004; 1680: 145-157.

Cowan, M. J., M. T. Gladwin and J. H. Shelhamer. "Disorders of Ciliary Motility." Am J Med Sci 2001; 321(1): 3-10.

Cowan, M. J., X. Huang, X. L. Yao and J. H. Shelhamer. "Tumor necrosis factor alpha stimulation of human Clara cell secretory protein production by human airway epithelial cells." Ann N Y Acad Sci 2000;. 923: 193-201.

Croft, D.R., Trapp, J., Kernstine, K., Krichner, P., Mullan, B., Galvin, J.R., FDG-PET imaging and the diagnosis of non-small cell lung cancer in region of high histoplasmosis prevalence Lung Cancer 2002;36(3):297-301.

Cross AS, Sakarya S, Rifat S, Held TK, Drysdale B-E, Grange PA, Cassels FJ, Wang L-X, Stamatos NM, Farese A, Casey D, Powell J, Bhattacharjee AK, Kleinberg M, and Goldblum SE. Recruitment of murine neutrophils in vivo through endogenous sialidase activity. J Biol Chem 2003, 278:4112-4120.

Cuesta, N., C. A. Salkowski, K. E. Thomas, and S. N. Vogel. Regulation of LPS Sensitivity by Interferon Regulatory Factor-2. J. Immunol. 2003;170: 5739-5747.

D. M. Paulnock and S. N. Vogel. Chapter 30: Macrophage Function. In: Textbook of Critical Care, E. Abraham (ed), Elsevier Science USA, Philadelphia. (in press, 2004).

Daun, J. M. and M. J. Fenton. IL-1/Toll Receptor Family Members: Receptor Structure and Signal Transduction Pathways. J. Interferon Cytokine Res. 2000; 20: 843-855.

DeLisle, S. Perl, T.M., Vancomycin-resistant enterococci: a roadmap on how to prevent the emergence and transmission of antimicrobial resistance. Chest 2003; 123:504S-518S

DeLisle, S., Perl, T.M., Antimicrobial management measures to limit resistance: A process-based conceptual framework. Crit Care Med 2001; (4 Suppl) N121-7

DeRenzo E, Silverman HJ, Hoffmann D, Schwartz J,. Maryland's Ethics Committee Legislation: A Leading Edge Model or A Step Into The Abyss. HEC Forum. 2001:13:49-58.

Do Boer ML, Hu J, Kalvakolanu DV, Hasday JD, Cross AS. IFN-gamma inhibits lipopolysaccharide-induced interleukin-1 beta in primary murine macrophages via a Stat1-dependent pathway. J. Interferon Cytokine Res. 2001: 21:485-94.

Dobrovolskaia M., and S. N. Vogel. TLRs as guards of cellular homeostasis: role in LPS signaling. Immunol. News 2001; October: 12 -15.

Dobrovolskaia, M., Medvedev, A.E.,, K. E. Thomas, N. Cuesta, V. Toshchakov, T. Ren, M. J. Cody, S.M. Michalek, N. R. Rice, and S. N. Vogel. Induction of in vitro reprogramming by TLR2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-?B signaling pathway components. J. Immunol. 2002; 170: 508-519.

Fairchild KD, Viscardi RM, Hester L, Singh IS, Hasday JD. Effect of hypothermia and hyperthermia on cytokine production by cultured human mononuclear phagocytes from adults and newborns. J. Interferon Cytokine Res. 2000; 20,1049-55.

Farzanfar R, Finkelstein J, Friedman RH. Testing the usability of two automated home-based patient management systems. J Medical Systems (in press).

Farzanfar R., Finkelstein J., Friedman R.H. Using qualitative research methods to improve home telemonitoring systems. Proceedings of the AMIA'2001 Annual Symposium. November 3-7, 2001, Washington, DC, 903.

Fasano A, Not T, Wang W, Uzzau S, Berti I, Tommasini A, and Goldblum SE. Zonulin, a newly discovered modulator of intestinal permeability and its expression in Coeliac Disease. Lancet 2000, 355:1518-1519.

Fenton, and S. N. Vogel. TLR2 and TLR4 agonists stimulate unique repertoires of host resistance genes in murine macrophages: Interferon-G-dependent signaling in TLR4-mediated responses. J. Endotoxin Res. (in press, 2003).

Fenton, M. J. Signal Transduction on the Fly. Nature Immunol. 2000; 1: 279-281.

Fessler, HE, Scharf SM, Permutt S. Improvement in spirometry following LVRS. Application of a physiologic model. Am J Resp Crit Care Med 2002; 165:34-40.

Finkelstein J, Feldman J, Safi C, Mitchell P, Khare R. The feasibility and patient acceptance of computer-assisted asthma education in Emergency Department setting. Proc. of the Academic Emergency Medicine 2003 Annual Meeting. Academic Emergency Medicine 2003;10:505.

Finkelstein J, Khare R, Vora D, Arora M. Design and implementation of Home Automated Telemanagement in Chronic Obstructive Pulmonary Disease. Proc. of the 16th IEEE Symposium on Computer-Based Medical Systems. June 26-27, 2003, New York, NY, 207-212.

Finkelstein J, Nyun, TM, Aronovitz JR, Khare R. A handheld interactive education tool for physicians to promote patient safety. Proceedings of the 26th Annual Meeting of the Society of General Internal Medicine. JGIM 2003; 18 (suppl 1): 108.

Finkelstein J, Shaya FT, Arora M, Joshi A, Samant N, Scharf SM. Automated survey collector (ASC): A universal Platform for interactive collection of clinical data. The 8^th World Multi-Conference on Systemics, Cybernetics and Informatatics, July 18 21, 2004 Orlando, FL.

Finkelstein J., Cabrera M., Hripcsak G. Internet-based Home Asthma Telemonitoring: Can patients handle the technology? Chest 2000; 117: 148-155.

Finkelstein J., Cabrera M., Hripcsak G. Patients' acceptance and self-testing validity in an Internet-based home asthma telemonitoring. Am J Respir Critical Care Med 1999; 159: A915.

Finkelstein J., Cabrera M., Potievski V. Analysis of asthma hospitalization trends in a low-income inner city area. Am J Respir Critical Care Med 1999; 159: A137.

Finkelstein J., Friedman R.H. Home Asthma Telemonitoring (HAT) system. Proceedings of the IEEE 26th Annual Northeast Bioengineering Conference. April 8-9, 2000, Storrs, Connecticut, 103-104.

Finkelstein J., Friedman R.H. Potential role of telecommunication technologies in the management of chronic health conditions. Dis Manage and Health Outcomes 2000; 8(2): 57-63.

Finkelstein J., Friedman R.H. Telecommunication offers solution for pulmonary disease management. Advance Manage Respir Care 2000; 9(5): 12-14.

Finkelstein J., Friedman R.H. Telemedicine system to support asthma self-management. Proceedings of 2000 IEEE EMBS International Conference on Information Technology Applications in Biomedicine. November 9-10, 2000, Arlington, Virginia, 164-167.

Finkelstein J., Friedman R.H., O'Connor G.T. Impact of Home Asthma Telemonitoring (HAT) in adult asthma patients. Proceedings of the American Telemedicine Association Fifth Annual Meeting. May 21-24, 2000, Phoenix, Arizona. Telemedicine J 2000; 6(1): 178.

Finkelstein J., Heeren T., Ash A. Distance to hospital and treatment of acute myocardial infarction. Proceedings of the AHA Scientific Forum: New Discoveries in Cardiovascular Disease and Stroke: Bench to Bedside to Community, Honolulu, HI, 2003, 37.

Finkelstein J., Hripcsak G., Cabrera M. Experience in building and implementation of a Web-based asthma telemonitoring program. Telemedicine J 1999; 5: A54.

Finkelstein J., Hripcsak G., Cabrera M. Knowledge discovery in a clinical information system to analyze patterns of asthma hospitalization. Proceedings of the AMIA'99 Annual Symposium. November 6-10, 1999, Washington, DC, 1057.

Finkelstein J., Khare R. Home Automated Telemanagement system to facilitate self-care of patients with chronic health conditions. Article accepted for a presentation at the 7th World Multi-Conference on Systemics, Cybernetics and Informatics. Orlando, FL, July 2003.

Finkelstein J., Khare R., Ansell J. Acceptance of Home Automated Telemanagement in patients on anticoagulation therapy. Proceedings of the ATS 2003 International Conference. Am J Respir Critical Care Med 2003; 167: A965.

Finkelstein J., Nambu S., Ansell J. Computer-assisted education for patients on anticoagulation therapy. International Journal of Behavioral Medicine 2002; 9(1suppl): 87-89.

Finkelstein J., Nambu S., Ansell J. Home Automated Telemanagement in patients on anticoagulation therapy. Proceedings of the 17th International Congress on Thrombosis. October 26-30, 2002, Bologna, Italy, 86.

Finkelstein J., Nambu S., Khare R., Gupta D. CO-ED: A development platform for interactive patient education. Proceedings of the International Conference on Computers in Education. December 3-6, 2002, Auckland, NZ, 648-650.

Finkelstein J., Nambu S., Khare R., Gupta D. Introducing handheld computing for interactive patient education. Proceedings of the AMIA'2002 Annual Symposium. November 9-13, 2002, San Antonio, TX, 1019.

Finkelstein J., O'Connor G.T., Fallon P., Plansky A., Friedman R.H. Information seeking and decision making preferences in asthma patients. Am J Respir Critical Care Med 2001; 163: A639.

Finkelstein J., O'Connor G.T., Friedman R.H. Development and implementation of the Home Asthma Telemonitoring (HAT) system to facilitate asthma self-care. Medinfo 2001, 10(pt 1): 810-814.

Finkelstein J., O'Connor G.T., Galichina N. Feasibility of Internet-based Home Automated Telemanagement in patients with Chronic Obstructive Pulmonary Disease. Chest 2001; 120(4suppl): 253S.

Finkelstein J., Posner M., Heeren T.C., Friedman R.H., Ash A. More intensive treatment of acute myocardial infarction reduces mortality. Proceedings of the 4th Scientific Forum on Quality of Care and Outcomes Research in Cardiovascular Disease and Stroke. October 13-14, 2002, Washington, DC, P156.

Fisher MR, Hassoun P, Criner G, Scharf S, Fessler HE. Accuracy of Doppler Echocardiography (DE) for pulmonary hypertension in the National Emphysema Treatment Trial (NETT). Am J Resp Crit Care Med 2004; 169: A178.

Fleming S.,, S. Toratani, T. Shea-Donohue, Y. Kashiwabara, S.N. Vogel, and E.S. Metcalf. Pro- and anti-inflammatory gene expression in the murine small intestine and liver after chronic exposure to alcohol. Alcohol Clin. Exp. Res. 2001; 25: 579-589.

Galvin JR, D'Alessandro MP. ElectricDiffuseLung: A Multimedia Textbook on Imaging of DIffuse Lung Disease. Iowa City, University of Iowa Electric Differential Multimedia Laboratory CD-ROM Publishing, 1993.

Galvin JR. The diagnosis of Pulmonary Embolus: A Clinicians Approach. Silver Platter Multimedia Education Series. 1994 Norwood MA.

Gao, J. J. ,V. Diesl, T. Wittmann, D. C. Morrison, J. L. Ryan, S. N. Vogel, and M. T. Follettie. Regulation of gene expression in mouse macrophages stimulated with bacterial CpG DNA and lipopolysaccharide. J. Leuk. Biol. 2002; 72: 1234-1245.

Gao, J. J., V. Diesl, T. Wittmann, D. C. Morrison, J. L. Ryan, S. N. Vogel, and M. T. Follettie. Regulation of gene expression in mouse macrophages stimulated with bacterial CpG-DNA and lipopolysaccharide. J. Leukoc. Biol. 2002; 72: 1234-1245.

Gladwin, M. T., X. L. Yao, M. Cowan, X. L. Huang, R. Schneider, L. R. Grant, C. Logun and J. H. Shelhamer. "Retinoic acid reduces p11 protein levels in bronchial epithelial cells by a posttranslational mechanism." Am J Physiol Lung Cell Mol Physiol 2000; 279(6): L1103-L1109.

Goldblum SE. Young BA, Wang P, and Murphy-Ullrich JE. Thrombospondin-1 induces tyrosine phosphorylation of adherens junction proteins and regulates an endothelial paracellular pathway. Mol Biol Cell 1999, 10:1537-1551.

Golenbock, D. T. and M. J. Fenton. Extolling the Virtues of Bacterial Endotoxins. Nature Immunol. 2001; 2: 286-288.

Golenbock. Toll-like Receptor 4 is the Target for Lipopolysaccharide Antagonists Accounting for Species-Specific Recognition of Lipid A Structures. J. Clin. Invest. 2000; 105: 497-504.

Greenberg HE, Sica A, Batson D, Scharf SM. Chronic intermittent hypoxia increases sympathetic responsiveness to hypoxia and hypercapnia. J Appl Physiol 1999; 86: 298 - 305.

Greenberg HE, Sica AL, Scharf SM, Ruggiero DA. Expression of c-fos in the rat brainstem after chronic intermittent hypoxia. Brain Res 1999; 816: 638 - 645.

Grieder F.B., and S. N. Vogel. Role of interferon and interferon regulatory factors in early protection against Venezuelan Equine Encephalitis Virus infection. Virology 1999; 257: 106-118.

Haehnel, V., L. Schwarzfischer, M. J. Fenton and M. Rehli. Transcriptional Regulation of the Human Toll-like Receptor 2 Gene in Mononuclear Phagocytes: Species-Specific Regulatory Sequences Controlling TLR2 Expression in Mouse and Man. J. Immunol. 2002; 168: 5629-5637.

Hasday JD and Garrison A. Antipyretic Therapy in Sepsis. Clin. Infect. Dis. 2000; 31:S234-42.

Hasday JD and Singh IS. Fever and the Heat Shock Response: Distinct, Partially Overlapping Processes. Cell Stress & Chaperones. 2000; 5:471-80.

Hasday JD and Singh IS. Fever and the stress response: Distinct, partially overlapping processes. Cell Stress Chaperones 2000; 5, 471-80.

Hasday JD, Bannerman D, Sakarya S, Cross AS, Singh IS; Howard D; Drysdaye B-E, and Goldblum SE. Exposure to febrile temperature modifies endothelial cell response to tumor necrosis factor-?. J Appl Physiol 2001, 90:90-98.

Hasday JD, Bannerman D, Sakarya S, Singh IS, Howard D, Drysdale B-E, Goldblum SE. Exposure to febrile temperature modifies endothelial cell response to tumor necrosis factor. J. Appl. Physiol 2001; 90, 90-98.

Hasday JD, Bannerman D, Sakarya S, Singh IS, Howard D, Drysdale B-E, and Goldblum SE. Exposure to Febrile Temperature Modifies Endothelial Cell Response to Tumor Necrosis Factor-a. J. Appl. Physiology. 2001; 90:90-98.

Hasday JD, Bascom R, Fitzgerald T, Dubin W. Bacterial endotoxin is an active component of mainstream and sidestream cigarette smoke. Chest 1999; 115:829-35.

Hasday JD, Fairchild K, Shanholtz C. The Influence of Fever on Survival in Sepsis. Microbes and Infection. 2000; 2:1891-1904.

Hasday JD, Garrison A, Singh IS, Standiford T, Ellis GS, Rao S, He JR, Rice P, Frank M, Goldblum SE, Viscardi RM. Febrile-range hyperthermia augments pulmonary neutrophil recruitment and amplifies pulmonary oxygen toxicity. Am. J. Pathol. 2003; 62: 2005-2017.

Hasday JD, Garrison A, Singh IS, Standiford T, Ellis GS, Rao S, He J-R, Rice P, Frank M, Goldblum SE, and Viscardi RM. Febrile-range hyperthermia augments pulmonary neutrophil recruitment and amplifies pulmonary oxygen toxicity. Am J Pathol 2003, 162:2005-2017.

Hasday JD, Meltzer SS, Wisniewski P, Bleecker ER. Anti-inflammatory effects of zileuton in a subpopulation of allergic asthmatics. Am J Respir Crit Care Med. 2000; 161:1229-36.

Heldwein, K. A. and M. J. Fenton. The Role of Toll-like Receptors in Immunity Against Mycobacterial Infection. Microbes Infect. 2002; 4: 937-944.

Heldwein, K. A., D. T. Golenbock, and M. J. Fenton. Recent Advances in the Biology of Toll-like Receptors. Mod. Asp. Immunobiol. 2001; 1: 249-252.

Heldwein, K. A., M. A. Armant, M. D. Liang T. K. Andresen, K. Thomas, S. N. Vogel, and M. J. Fenton. TLR2 and TLR4 Serve Distinct Roles in the Host Immunity Against Mycobacterial Antigens. J. Leuk. Biol. (in press, 2003).

Heldwein, K. A., M. A. Armant, M. D. Liang, T. K. Andresen, K. Thomas, A. Marty, S. N. Vogel, and M. J. Fenton. TLR2 and TLR4 serve distinct roles in the host response against mycobacterial infection. J. Leukocyte Biology (in press, 2003).

Hey, JC, Scharf, SM. Pulmonary arterial hypertension - the primary pulmonary hypertension syndromes. IMAJ 2003; 5: 298-303.

Hirschfeld, M. ,J. J. Weis, V. Toshchakov, C.A. Salkowski, M.J. Cody, D.C. Ward, N. Qureshi, S.M. Michalek, and S.N. Vogel. Signaling by TLR2 vs. TLR4 agonists results in differential gene expression in murine macrophages. Infect. Immun. 2001; 69: 2477-2482.

Hirschfeld, M., Y. Ma, J.H. Weis, S.N. Vogel, and J.J. Weis. Cutting Edge: Repurification of LPS eliminates signaling through both human and murine Toll-like receptor 2000; 2. J. Immunol. 165: 618-622.

Hisatsune A, Hyun SW, Lee IJ, Georas SN, Kim KC. YY1 Transcription Factor is Not Responsible for the Negative Regulation of Hamster Muc1 Transcription. Anticancer Res 2004; 24:235-240.

Huang, X.-L., R. Pawliczak, M. J. Cowan, M. T. Gladwin, P. Madara, C. Logun and J. H. Shelhamer. "Epidermal growth factor induces p11 gene and protein expression and down-regulates calcium ionophore-induced arachidonic acid release in human epithelial cells." J Biol Chem 2002; 277 (41): 38431-38440.

Huang, X.-l., R. Pawliczak, X.-l. Yao, M. J. Cowan, M. T. Gladwin, M. J. Walter, M. J. Holtzman, P. Madara, C. Logun and J. H. Shelhamer. "Interferon-g Induces p11 Gene and Protein Expression in Human Epithelial Cells through Interferon-g-activated Sequences in the p11 promoter." J BiolChem 2003; m278(11): 9298-9308.

Huang, X.-l., R. Pawliczak, X.-l. Yao, P. Madara, S. Alsaaty, J.H. Shelhamer and M.J. Cowan. "Characterization of the human p11 promoter sequence." Gene, 2003 in press.

Hunninghake G, Lynch DA, Galvin JG, Gross B, Muller N, Zimmerman MB, Schwartz DA. Radiological findings are strongly associated with the pathological diagnosis of IPF. Chest 2003; 124:1215-1223.

Hunsaker A, Ingenito E, Topal U, Pugatch RD, Reilly J. Preoperative screening for lung volume reduction surgery: utility of combining thin section CT with physiologic assessment. AJR 1998;170(2)309-14.

I. S. Singh, J. R. He, L. Hester, M. J. Fenton, and J. D. Hasday. Bacterial endotoxin modifies heat shock factor-1 activity in RAW 264.7 cells: implications for TNF-a regulation during exposure to febrile range temperatures. J. Endotoxin Res. 10: 175-84, 2004.

Iadecola C., C.A. Salkowski, F. Zhang, T. Aber, M. Nagayama, S.N. Vogel, and M.E. Ross. The transcription factor Interferon Regulatory Factor-1 is expressed after cerebral ischemia and contributes to ischemic brain injury. J. Exp. Med. 1999; 189: 719-727.

Iqbal M, Rossoff L, McKeon K, Graver LM, Scharf SM. Development of a giant bulla after lung volume reduction surgery. Chest 1999; 116:1809-1811.

J. C. G. Blanco, M. Boukhvalova, L. Pletneva, G. A. Prince, and S. N. Vogel. Re-thinking respiratory syncytial virus vaccines. Recent Research Developments in Experimental Medicine (in press, 2004).

Jiang Q, Cross AS, Singh IS, Chen TT, Viscardi RM, Hasday JD. Febrile core temperature is essential for optimal host defense in bacterial peritonitis. Infect Immun. 2000; 68: 1265-1270.

Jiang Q, Cross AS, Singh IS, Chen TT, Viscardi RM, Hasday JD. Febrile Core Temperature is Essential for Optimal Host Defense in Bacterial Peritonitis. Infect. Immun 2000; 68:1265-70.

Jiang Q, Detolla L, Kalvakolanu I, Fitzgerald B, Van Roojien N, Singh IS Hasday JD. Febrile-range temperature modifies early systemic TNF? expression in bacterial endotoxin-challenged Mice. Infect. Immun. 1999; 67:1539-46.

Jiang Q, Detolla L, Singh IS, Gatdula L, Fitzgerald B, van Rooijen N, Cross AS, Hasday JD. (1999) Exposure to febrile temperature upregulates expression of pyrogenic cytokines in endotoxin-challenged mice. Am J Physiol. 1999; 276: R1653-1660.

Jiang Q, Detolla L, Singh IS, Gatdula L, Fitzgerald B, Van Rooijen N, Cross AS, Hasday JD. Exposure to febrile temperature upregulates expression of pyrogenic cytokines in endotoxin-challenged mice. Am. J. Physiol. 1999; 276:R1653-60.

Jiang Q, DeTolla L, van Rooijen N, Singh IS, Fitzgerald B, Lipsky MM, Kane AS, Cross AS, Hasday JD. Febrile-range temperature modifies early systemic tumor necrosis factor alpha expression in mice challenged with bacterial endotoxin. Infect Immun. 1999; 67: 1539-46.

Jo M, Shin CY, Song MR, Park KH, Seo DO, Choi EY, Kim KC, Ko KH. A monoclonal antibody against hamster tracheal mucin, which recognizes N-acetyl-galactosamine containing carbohydrate chains as an epitope. Hybridoma 1999; 18: 449-456.

Jones, B. W., K. A. Heldwein, T. K. Means, J. J. Saukkonen, and M. J. Fenton. Differential Roles of Toll-like Receptors in the Elicitation of Pro-Inflammatory Responses by Macrophages. Ann. Rheum. Dis. 2001; 60: iii6-iii12.

Jones, B. W., T. K. Means, K. A. Heldwein, M. A. Keen, P. J. Hill, J. T. Belisle, and M. J. Fenton. Different Toll-like Receptor Agonists Induce Distinct Macrophage Responses. J. Leuk. Biol. 2001; 69: 1036-1044.

Joshi VD, Kalvakolanu DV, Hasday JD, Hebel RJ, Cross AS. IL-18 levels and the outcome of innate immune response to LPS: importance of a positive feedback loop with caspase-1 in IL-18 expression. J Immunol. 2002:169:2536-44.

Joshi VD, Kalvakolanu DV, Hebel RJ, Hasday JD, Role of caspase 1 in murine antibacterial host defenses and lethal endotoxemia. Infect Immun. 2002:70:6896-903.

Kantakamalakul W.,, A.D. Politis, S. Marecki, T. Sullivan, K. Ozato, M. Fenton, and S.N. Vogel. Regulation of Interferon Consensus Sequence Binding Protein (ICSBP) in Murine Macrophages. J. Immunol. 1999; 162: 7417-7425.

Kantakamalakul, W., A. D. Politis, S. Marecki, T. Sullivan, K. Ozato, M. J. Fenton, and S. N. Vogel. Regulation of Interferon Consensus Sequence Binding Protein (ICSBP) Expression in Murine Macrophages. J. Immunol. 1999; 162: 7417-7425.

Kim KC, Gleich GJ, Lee MK. Two eosinophil granule proteins, eosinophil peroxidase and major basic protein, inhibit mucin release from airway goblet cells. Inflamm Res 1999; 48:314-317.

Kim KC, Hisatsune A, Kim DJ, Miyata T. Pharmacology of airway goblet cell mucin release. J Pharm Sci (2003 in press)

Kim KC, Hisatsune A, Kim DJ, Miyata T. Pharmacology of airway goblet cell mucin release. J Pharmacol Sci 2003; 92: 301-307.

Kim KC, Hyun SW, Kim BT, Meerzaman D, Lee MK, Lillehoj E. 2001. Pseudomonas adhesion to MUC1 mucins: A potential role of MUC1 mucins in clearance of inhaled bacteria. In, Cilia, Mucus and Mucociliary Interactions. M. Salathe (ed). Marcel Dekker, Inc., pp. 217-224.

Kim KC, Hyun SW, Kim BT, Meerzaman D, Lee MK, Lillehoj E. 2001. Pseudomonas adhesion to MUC1 mucins: A potential role of MUC1 mucins in clearance of inhaled bacteria. In, Cilia, Mucus and Mucociliary Interactions. M. Salathe (ed). Marcel Dekker, Inc., pp. 217-224.

Kim KC, Lee BC, Pou S, Ciccolella D. Effects of activation of polymorphonuclear leukocytes on airway goblet cells mucin release in a co-culture system. Inflammation Res 2003; 52:258-262.

Ko KH, Lee CJ, Shin CY, Kim KC. Inhibition of mucin release from airway goblet cells by polycationic peptides. Am J Physiol 1999; 277:L811-815.

Kopydlowski K.M.,, C.A. Salkowski, M. J. Cody, N. van Rooijen, J. Major, T. A. Hamilton, and S. N. Vogel. Regulation of macrophage chemokine expression by lipopolysaccharide in vitro and in vivo. J. Immunol. 1999; 163: 1537-1544.

Kozlov, S. V., M. A. Dobrovolskaia, N. R. Rice, C. L. Stewart, and S. N. Vogel. A novel cell-based system for the rapid quantitative evaluation of (anti)-inflammatory potential of test-subtances. J. Immunol. Methods (in press, 2003).

Lakics V.,, A.E. Medvedev, S. Okada, and S.N. Vogel. Inhibition of LPS-induced cytokines by Bcl-xL in a murine macrophage cell line. J. Immunol. 2000; 165: 2729-2737.

Lee CJ, Paik SH, Ko KH, Kim KC. Polycationic peptide-induced mucin release from airway goblet cells: Relationship between the polymer size and the activity. Inflammation Res 2002; 51:490-494.

Lee IJ, Han F, Baek J, Hisatsune A, Kim KC. Inhibition of muc1 expression by indole-3-carbinol. Int J Cancer 2004; 109:810-816.

Lee IS, Hyun SW, Nandi A, Kim KC. Transcriptional regulation of the hamster Muc1 gene: Identification of a putative negative regulatory element Am J Physiol 2003; 284: L160-L168.

Lee IS, Hyun SW, Nandi A, Kim KC. transcriptional regulation of the hamster Muc1 gene: Identification of a putative negative regulatory element Am J Physiol 2003; 284: L160-L168.

Lillehoj EP, Han F, Kim KC. Mutagenesis of a Gly-Ser cleavage site in MUC1 inhibits ectodomain shedding. Biochem Biophys Res Comm 2003; 307:743-749.

Lillehoj EP, Han F, Kim KC. MUC1 Shedding Due to Subunit Dissociation. Biochem Biophy Res Comm. (2003 in press).

Lillehoj EP, Hyun SW, Kim BT, Zhang XG, Lee DI, Rowland S, Kim KC. MUC1 mucins on the cell surface are adhesion sites for Pseudomonas aeruginosa. Am J Physiol 2001; 280:L181-L187.

Lillehoj EP, Hyun SW, Kim BT, Zhang XG, Lee DI, Rowland S, Kim KC. MUC1 mucins on the cell surface are adhesion sites for Pseudomonas aeruginosa. Am J Physiol 2001; 280:L181-L187.

Lillehoj EP, Kim BT, Kim KC. Identification of Pseudomonas aeruginosa flagellin as an adhesin for Muc1 mucin. Am J Physiol 2002; 282:L751-L756.

Lillehoj EP, Kim H, Chun EY, Kim KC. Pseudomonas aeruginosa Stimulates Phosphorylation of the Epithelial Membrane Glycoprotein Muc1 and Activates MAP Kinase. Am J Physiol (Lung Cell Mol Physiol) 2004; 287:L809-L815.

Lillehoj EP, Kim KC. Airway mucus: Its components and function. Arch. Pharm. Res. 2002; 25:770-780.

Lu, W., Lillehoj, E.P., Kim, K.C. 2004. Effects of Dexamethasone on Muc5ac Mucin Production by Primary Airway Goblet Cells. Am J Physiol (Lung Cell Mol Physiol) 10.1152/ajplung.00104.2004 (published on line, September 10, 2004)

M. D. Liang, A. Bagchi, H. S. Warren, M. M. Tehan, J. A. Trigilio, L. K. Beasley-Topliffe, B. L. Tesini, J.-C. Lazzaroni, M. J. Fenton, and J. Hellman. Bacterial Peptidoglycan-Associated Lipoprotein is a Naturally Occurring Toll-like Receptor 2 Agonist that is Shed into Serum and is Synergistic with LPS. J. Infect. Dis. (in press, 2004).

Macko RF, Gelber AC, Young BA, Lowitt MH, White B, Wigley FM, and Goldblum SE. Increased circulating levels of the counteradhesive proteins, SPARC and thrombospondin-1 in systemic sclerosis (Scleroderma): Relationship to platelet and endothelial cell activation. J Rheumatol 2002, 29:2565-2570.

Magder S and Scharf SM. Venous Return. In Scharf SM, Pinsky MR, Magder S (esd). Respiratory-Circulatory Interactions in Health and Disease. MarcelDekker, Inc., New York, 2001, pp.93 = 112.

Manimtim WM, Hasday JD, Hester L, Fairchild KD, Lovchik JC, Viscardi RM. Ureaplasma urealyiticum Modulates Endotoxin-induced Cytokine Release by Human Monocytes Derived from Preterm and Term Newborns and Adults. Infect. Immun. 2001: 69:3906-15.

Marecki, S. and M. J. Fenton. PU.1/Interferon Regulatory Factor Interactions: Mechanisms of Transcriptional Regulation. Cell Biochem. Biophys. 2000; 33: 101-121.

Marecki, S. and M. J. Fenton. The Role of IRF-4 in Transcriptional Regulation. J. Interferon Cytokine Res. 2002; 22:121-33.

Marecki, S., M. D. Liang, C. Reindeau, and M. J. Fenton. PU.1 and Multiple IRF Proteins Synergize to Mediate Transcriptional Activation of the Human IL-1? Gene. J. Immunol. 2001; 166: 6829-6838.

Marecki, S., M. L. Atchison, and M. J. Fenton. Differential Expression and Distinct Functions of Interferon Consensus Binding Protein and Interferon Regulatory Factor 4 in Macrophages. J. Immunol. 1999; 163: 2713-2722.

Martin M., J. Katz, S. N. Vogel, and S. M. Michalek. Differential induction of endotoxin tolerance by lipopolysaccharides derived from Porphyromonas gingivalis and Escherichia coli.. J Immunol. 2001; 167:5278-85.

Martin, M., R. E. Schifferle, N. Cuesta, S. N. Vogel, J. Katz, and S. M. Michalek. Role of the PI3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide. J. Immunol. (in press, 2003).

Martinez, F. J., R. L. Strawderman, K. R. Flaherty, M. Cowan, J. B. Orens and J. Wald (1999). "Respiratory response during arm elevation in isolated diaphragm weakness." Am J Respir Crit Care Med 160(2): 480-486.

Means T. K.,, B. W. Jones. B A. Sjurtleff, J. A. Smith, J. Keane, D. T. Golenbock, S.N. Vogel, and M. J. Fenton. Differential effects of a Toll-like receptor antagonist on M. tuberculosis-induced macrophage responses. J. Immunol. 2001; 166: 4074-4082.

Means, T. K., B. W. Jones, A. B. Schromm, B. A. Shurtleff, J. A. Smith, J. Keane, D. T. Golenbock, S. N. Vogel, and M. J. Fenton. Differential Effects of a Toll-Like Receptor Antagonist on Macrophage Responses to M. tuberculosis. J. Immunol. 2001; 166: 4074-4082.

Means, T. K., D. T. Golenbock, and M. J. Fenton. The Biology of Toll-like Receptors. Cytokine Growth Factor Rev. 2000; 11: 219-232.

Means, T. K., D. T. Golenbock, and M. J. Fenton. The Structure and Function of Toll-like Receptors. Life Sci. 2000; 68: 241-258.

Means, T. K., E. Lien, A. Yoshimura, S. Wang, D. T. Golenbock, and M. J. Fenton. The CD14 Ligands Lipoarabinomannan and Lipopolysaccharide Differ in Their Requirement for Toll-like Receptors. J. Immunol. 1999; 163: 6748-6755.

Means, T. K., R. P. Pavlovich, D. Roca, M. W. Vermeulen, and M. J. Fenton. Activation of TNF-A Transcription Utilizes Distinct MAP Kinase Pathways in Different Macrophage Populations. J. Leuk. Biol. 2000; 67: 885-893.

Means, T. K., S. Wang, E. Lien, A. Yoshimura, D. T. Golenbock, and M. J. Fenton. Human Toll-like Receptors Mediate Cellular Activation by M. tuberculosis. J. Immunol. 2000; 163: 3920-3927.

Means, T. K., T. A. Lodie, and M. J. Fenton. Activation of Protein Kinase CK2 by LPS is Mediated by the MAP Kinase Pathway. J. Endotoxin Res. 1999; 5: 37-40.

Medvedev A. E., and S. N. Vogel. Overexpression of CD14, TLR4, and MD-2 in HEK 293 cells does not prevent induction of in vitro endotoxin tolerance. J Endotoxin Res 2003; 9: 60-64.

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