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Anatomy
of the Skin
What is the skin?
The skin is the outer covering of the body. It is the body's largest organ, and weighs
about 6 pounds.

Skin is made up of three main layers:
The outer layer: epidermis
Made up of three sub-layers:
the outer-most layer - the stratus corneum (or horny
layer) contains continually shedding, dead keratinocytes (the primary cell type of the
epidermis).
the middle layer - contains layers of living keratinocytes
(also called squamous cells). Keratin, a protein formed by these cells,
helps provide the skin what it needs to protect the rest of the body.
the inner layer - the basal layer that contains basal
cells. Basal cells continually divide, forming new keratinocytes and replacing the old
ones that are shed from the skin's surface.
Also contained in the epidermis:
melanocytes - a type of cell that resides in the epidermis that
produces melanin (a protective pigment that gives the skin its color).
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The middle layer: dermis
Made up of the following, which are all held together by a protein called collagen:
- blood vessels
- lymph vessels
- hair follicles
- sweat glands
collagen - made by fibroblasts (skin cells that give the skin its
strength and resilience).
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The deepest layer: subcutis
Also known as the subcutaneous layer, the
subcutis forms a network of collagen and fat cells.
The subcutis is responsible for conserving the body's heat, while helping to protect the
organs of the body from injury by acting as a "shock-absorber".
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What are the functions of the skin?
The primary functions of the skin are to protect the body against heat, light,
injury and infection; to store water, fat, and vitamin D; and to regulate the body's
temperature.
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