Melanoma
What is melanoma?
Melanoma is a disease of the skin in which cancer cells are found in the
melanocytes, the cells that produce color in the skin or pigment known as melanin.
Melanoma usually occurs in adults, but it may occasionally be found in children and
adolescents. Melanoma may also be called cutaneous melanoma or malignant melanoma.
Melanoma is the rarest, but most virulent, form of skin cancer.
Melanoma is a more serious type of cancer than the more common basal cell cancer, or
squamous cell cancer. Although the incidence of melanoma is lower than other types of skin
cancer, it has the highest death rate and is responsible for 75 percent of all deaths from
skin cancer.
Where is melanoma most often found?
Melanoma most often appears on fair-skinned men and women, but people with other skin
types can be affected. Rarely, melanomas can form in parts of the body not covered by skin
such as the eyes, mouth, vagina, large intestine, and other internal organs.
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What is a risk factor? A risk factor is anything that may increase a person’s chance of
developing a disease. It may be an activity, such as smoking, diet, family history, or
many other things. Different diseases, including cancers, have different risk factors.
Although these factors can increase a person’s risk,
they do not necessarily cause the disease. Some people with one or more risk factors never
develop the disease, while others develop disease and have no known risk factors.
But, knowing your risk factors to any disease can help to
guide you into the appropriate actions, including changing behaviors and being clinically
monitored for the disease. |
What are the risk factors for melanoma?
Persons with the following characteristics may be at an increased risk
for melanoma:
blond or red hair
blue eyes
fair complexion
family history of melanoma
a changed or changing mole
many ordinary moles (more than 50)
many freckles
an immunosuppressive disorder
dysplastic nevi
sun exposure
The amount of time spent unprotected in
the sun directly affects your risk of skin cancer.
inability to tan
Dark-brown or black skin is not a guarantee against melanoma.
African-Americans can develop this cancer, especially on the palms of the hands, soles of
the feet, under nails, or in the mouth.
What are the symptoms of melanoma?
The following are the most common symptoms of melanoma. However, each individual may
experience symptoms differently. Symptoms may include:
-
change in the size, shape, or color of a mole
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oozing or bleeding from a mole
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a mole that feels itchy, hard, lumpy, swollen, or tender to the touch
Because most malignant melanoma cells still produce melanin, melanoma tumors are often
shaded brown or black. Melanoma can also appear on the body as a new mole. Men most often
develop melanoma on the area of the body between the shoulders and hips, or on the head or
neck. Women most often develop melanoma on the arms and legs. However, melanoma can spread
quickly to other parts of the body through the lymph system, or through the blood. Like
most cancers, melanoma is best treated when it is diagnosed early.
The symptoms of melanoma may resemble other conditions or medical problems.
Always consult your physician for a diagnosis.
Distinguishing benign moles from melanoma:
To prevent melanoma, it is important to examine your skin on a regular
basis, and become familiar with moles, and other skin conditions, in
order to better identify changes. According to recent research, certain
moles are at a higher risk for changing into malignant melanoma. Moles
that are present at birth, and atypical moles, have a greater chance of
becoming malignant. Recognizing changes in your moles, by following this ABCD
Chart, is crucial in detecting malignant melanoma at its
earliest stage. The warning signs are:
| Normal Mole |
Melanoma |
Sign |
Characteristic |
 |
 |
Asymmetry |
when
half of the mole does not match the other half |
 |
 |
Border |
when
the border (edges) of the mole are ragged or irregular |
 |
 |
Color |
when
the color of the mole varies throughout |
 |
 |
Diameter |
if
the mole’s diameter is larger than a pencil’s eraser |
| Photographs Used By
Permission: National Cancer Institute |
Melanomas vary greatly in appearance. Some melanomas may show
all of the ABCD characteristics, while other may only show changes in
one or two characteristics. Always consult your physician for a
diagnosis.
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