Obstetrics, Gynecology and Reproductive Health
Maternal Fetal Medicine Fellowship Program
Graduate Course Descriptions
List of Courses
| PREV 621 |
Biostatistical Methods* |
3 Credits |
| HGEN 728 |
Clinical Genetics* |
2 Credits |
| PREV 633 |
Legal and Regulatory Issues in Clinical Research* |
1 Credit |
| HGEN 620 |
Introduction to Genetic Counseling |
2 Credits |
| PREV 619 |
Biostatistical Computing |
1 Credit |
| PREV 637 |
Ethical Issues in Clinical Research |
3 Credits |
| PREV 720 |
Statistical Methods in Epidemiology |
3 Credits |
| PREV 721 |
Regression Analysis |
2 Credist |
| PREV 803 |
Clinical Trials and Experimental Expidemiology |
3 Credits |
| HGEN 731 |
Clinical Genetics |
2 Credits |
Classes indicated by an asterisk (*) are required courses. PREV 621 and one of the
other courses fulfill the post-graduate course requirement.
NOTE: This list is representative. The complete catalogue of UMB graduate level
courses is available to the fellows.
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Description of Courses
- PREV 621 Biostatistical Methods*: This course is designed to introduce the
students to a broad range of methods commonly used in biomedical and public health research, and
to provide some hands-on data analysis experi¬ence. Topics to be covered include the role of
statistics in science, properties of distributions, exploratory data analysis, inference about
means, proportions and survival distributions, and introduc¬tion to multivariable methods.
Note: PH 621/ PREV 621 does not satisfy the biostatistical requirements for MS
or PhD students in Epidemiology, but is an appropriate course for other graduate degree
programs.
- HGEN 728 Clinical Genetics*: Topics in this course include collection and
interpretation of pedigree information, determination of modes of inheritance, calculation of
recurrence risks, techniques of genetic counseling, and an introduction to genetic nosology.
Students also gain practical experience in the genetic counseling clinics and on hospital ward
consultative rounds, with extensive training in abstracting patient medical histories, writing
evaluation reports to be co-signed by faculty, and interpreting laboratory results.
Prerequisites: HGEN 601 and HGEN 602 or equivalent.
- PREV 633 Legal And Regulatory Issues In Clinical Research*: The course will be
co-taught by faculty from the School of Medicine and the School of Nursing. The course is
required for the Master of Science in Clinical Research in the School of Medicine and the Master
of Science in Clinical Research Management in the School of Nursing. This mixture of students
will promote the multidisciplinary interactions integral to successful clinical research.
Prerequisites: Health professional degree and clinical research experience.
- HGEN 620 Introduction to Genetic Counseling I: This course is designed to
introduce the principles of the field of genetic counseling. This lecture series will cover the
history behind the development of genetic counseling as a profession and the concepts of
nondirectiveness and patient autonomy will be emphasized through the course. In addition,
applications of genetic counseling in medical care will be demonstrated, with special attention
to the psychosocial aspects of the field. This course is designed to complement HGEN 728,
Clinical Genetics I, and along with HGEN 621, will help prepare students for clinical rotations
the following year.
- PREV 619 Biostatistical Computing: Provides the student with comprehensive
experience in the application of epidemiological and biostatistical methods available in the
Statistical Analysis System (SAS). Hands-on experience in weekly workshops is gained by
conducting analyses of existing data designed to answer a research question.
Prerequisites: PREV 620 (Principles of Biostatistics), or Instructor's
permission and knowledge of basic principles of epidemiology.
- PREV 637 Ethical Issues in Clinical Research: This course begins with the birth
of contemporary bioethics in famous research scandals and ends with some current problems on the
cutting edge of scientific research ethics. In between, we shall examine the regulatory structure
designed to curb the abuse of patient/subjects; specifically, this will consist of the role and
functions of institutional review boards (IRBs). The approach will be primarily philosophical but
with attention to history and regulation. Many of the great cases (such as the Nazi Doctors'
Trial, the Tuskegee syphilis study, Willowbrook, Milgram's authority experiments, and the
recently revealed U.S. government-sponsored radiation studies) will be examined with an eye both
to historical detail and to ethical analysis. The course will emphasize controversies concerning
the ethical design of research studies (e.g., randomization, placebos, informed consent,
coercive induce¬ments, gauging risk and benefit, etc.) as well as problems posed by specific
"subject populations" such as medical students, prisoners, developing-world subjects, and
cognitively impaired patients. Throughout the course, we will have practical experiences in the
ethical review of research protocols.
- PREV 720 Statistical Methods in Epidemiology: Provides instruction on the
specific statistical techniques used in the analysis of epidemiological data. Topics include:
treatment of stratified and matched data, detection of interaction, conditional and unconditional
logistic regression, survival analysis, and proportional hazards model.
Prerequisites: PREV 600, PREV 620 and consent of instructor.
- PREV 721 Regression Analysis: Covers basic principles and theory of regression
techniques. Topics include simple and multiple linear regression, robust regression, regression
diagnostics, logistic and Poisson regression analysis. The emphasis of this course is on learning
the biomedical research application and interpretation of regression techniques.
Prerequisites: PREV 620 or consent of instructor.
- HGEN 731 Clinical Genetics: This course is designed to complement HGEN 730, and
covers all clinical aspects of genetic disease. This lecture series will cover specific genetic
disorders and birth defects, organ systems, and both metabolic and dysmorphic syndromes. Normal
prenatal and pediatric development will be reviewed to give the student a better understanding of
the disease process. In addition, medical terminology, components of medical charts and physical
examinations, and the organizations and administration of medical centers will be covered.
A basic introduction to other specialties and subspecialties will also be included, as most
genetic disorders involve coordination of complex medical care.
Prerequisite: HGEN 730 or equivalent.
Classes indicated by an asterisk (*) are required courses. PREV 621 and one of the
other courses fulfill the post-graduate course requirement.
NOTE: This list is representative. The complete catalogue of UMB graduate level
courses is available to the fellows.
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Method of Documenting a Passing Grade
Once courses are completed, grades are distributed through the Registrar's office and available
online. The fellow provides the program director with a copy of the grade, which is then
maintained in the fellow's official file.
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This page was last updated on: April 26, 2010.
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