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Obstetrics, Gynecology and Reproductive Health

Maternal Fetal Medicine Fellowship Program

Educational Objectives | Didactic Conferences | Clinical Facilities | Special Areas | Research | Department Fellows

Research

 

Facilities

The Department of Obstetrics, Gynecology, and Reproductive Sciences maintains its basic research facilities on the 11th floor of the Bressler Building. This facility consists of approximately 15,000 square feet of wet laboratory space and is linked to the main hospital by corridors. The space is shared by the basic scientists already noted. The equipment contained therein is state of the art and allows for a full range of studies ranging from sophisticated molecular biology to whole animal instrumentation.

Research Time

This fellowship program was created on the principle of block time. There are 18 months dedicated to didactics and research. It is expected that this volume of research time will allow all fellows to design and conduct research of sufficient quality to assure completion of the thesis prior to graduation from the fellowship. When assigned to the core MFM clinical service, the Fellow will be scheduled for clinical activities at least 8 half-days per week. The remainder of the time, clinical activity permitting, may be spent in the laboratory. All fellows participate in a one week Introduction to Clinical Research at UMB course given under the direction of the Department of Epidemiology and Preventive medicine. As noted above in order to provide a better foundation as well as an earlier start for research, the first year of our program has been redesigned. The initial four months provide an introduction to ultrasound, and genetics as previously described. The final month of is devoted to an introduction to basic science research under the direction of Loren Thompson PhD. at the beginning of the first research block in the first year

When assigned to a research month the Fellows’ research shall be interrupted only by didactic sessions and attending the resident High Risk Clinic (one-half day each per week). These clinical activities total six hours/week, well within the 10% time limit allowed. Night call remains constant throughout the Fellowship as described above.

Occasional cross coverage for critical clinical activities may be required of one Fellow for another’s vacation or attendance at scientific or didactic meetings. This is reciprocated in kind to protect total research time.

Library, Literature Search Programs, Databases, Medical Records

Members of the Department of Obstetrics, Gynecology, and Reproductive Sciences at the University of Maryland are linked together by a Hospital Intranet with full access to the Internet. The fellows have access to several interactive or archival databases. We have completed the process of transitioning our complete obstetric record from an old and now obsolete text based “ProTouch” system to a new Windows NT based system wide computerized medical record which cross populates directly into our perinatal database. The Fellows have access to queriable periodic downloads from this archival database, and after IRB approval can obtain specific queries as well. All neonatal data is likewise maintained on an archival database. Interactive databases include a perinatal genetics database, an obstetric outcome database, and the database for the Center for Advanced Fetal Care.

These databases are linked by a universal medical record number, and social security number and patient birth-date. They are all compatible with commercial relational databases and spreadsheets, which are made available to the Fellows on their individual (supplied by the department) PCs. Data stored on the network servers are automatically backed up on a daily basis.

Assistance in query design, database construction, and data analysis is provided by MFM faculty (Drs. Ahmet Baschat MB BCh and his Post Doctoral Research Assistant Dr. Ozhan Turan M.D., Ph.D) and members of the Department and Information Technology Team. Further assistance is available from the extensive information management and computer resources available within the University.

The Fellows also have access to several research databases maintained by members of the faculty including fetal transfusions, and fetal blood samplings, and pregnancies complicated by fetal viral infections, severe IUGR and Fetal Doppler. The fellows also maintain and have access to databases initiated by previous fellows’ research in GDM, PPROM, and Trauma. These databases are compatible with the Fellows’ retrieval and analysis software and can be used by the Fellows to research relevant topics. Finally, the Fellows have on-line access to all medical records after approval by the Committee for Human Investigation should they wish to conduct clinical research.

From their offices, Fellows have access to the internet, the University intranet, and The University of Maryland Health Sciences Library. The University of Maryland School of Medicine Library is located across the street from the UMMS. The Library is the second largest medical school library on the East Coast and serves as the Regional Medical Library for the Southeastern Atlantic Region in the National Library of Medicine’s National Network of Libraries of Medicine. The University Library allows access to 93 on-line databases and over 2800 online journals and textbooks, including, AIDSLINE, BioethicsLine, CancerLit, Cochrane Library, Current Contents Connect (CCC), ETOH (Alcohol and Alcohol Problems Science Database), Journal Citation Reports, MD Consult, MEDLINE , Micromedex, PubMed, PsycINFO, Science Citation Index Expanded, TOXNET (Toxicology Data Network). A state of the art teleconference center is also located within the departmental library.

Specific consultation on statistical issues, study design, and analysis is available through the UMB School of Epidemiology. Assistance with and further training in research and study design, and implementation are available through the UM SOM Office for Research Subjects and The Dean’s Office.

Selection of special mentor

The selection of a research mentor for each Fellow is the responsibility of the Program Director. This selection takes place within the first three to sixth months of the Fellowship and is subject to the approval of the fellow. The research mentor is responsible for ensuring the progress of each Fellow's research project(s).

Current Research

  1. Second trimester maternal biochemical markers and uterine artery Doppler velocimetry in the prediction of pre-eclampsia: A retrospective study.
    Harman C, Blitzer M, Baschat A, Kush M, Adams L, Staney R, Kopelman J, Atlas R.

  2. Combined first trimester ultrasound screening for fetal malformations in pregestational diabetes using nuchal translucency thickness, ductus venosus Doppler and serum hemoglobin A1CHarman C, Weiner C, Baschat A, Kush M, Manogura A.

  3. Computerized fetal heart rate monitoring in preterm premature rupture of membranes. Harman C, Alger L, Baschat A, Oh C, Kush M, Manogura A, Iqbal S.

  4. Ultrafast MRI's and prenatal diagnosis. Harman C, Weiner C, Wong J, Hosseinzadeh K, Baschat A, Oh C.

  5. First trimester prediction of placental dysfunction by evaluation of maternal hemodynamics and pregnancy-specific serum markers Baschat A, Harman C, Kush M, Atlas R

  6. Steroids in the treatment of severe pre-eclampsia. Alger L, Oh C, Harman C, Kopelman J, Mighty H.

  7. Fetal monitoring in IUGR: relating biophysical parameters and Doppler evaluation to perinatal outcome. Harman C, Baschat A, Kush M

  8. Outcome of pregnancies with absent ductus venosus flow with normal nuchal translucency in the first trimester. Harman C, Baschat A, Oh C.

  9. Maternal HIV status and neonatal outcomes. Iqbal S, Turan O, Kriebs J, Alger L, Yazdani M, Baschat A, Harman C.

  10. Chronic hypoxia model in the pregnant guinea pig. Oh C, Dong Y, Thompson L, Departmental funding

Fellow's Presentations and Papers

  1. Muench, Michael 2002
    1. Presentations
      1. Muench, M; Baschat, A; Harman, C; Mighty, H. Elevated White Blood Cell Count in Maternal Trauma: Does it Predict Placental Abruption?. 24nd Annual Meeting Of The Society For Maternal-Fetal Medicine, New Orleans La, 2/4/04 -2/07/04.
      2. Muench, M; Baschat, A; Kush, M; Mighty,H; Harman, C. Maternal Fetal Hemorrhage of Greater than or Equal to 0.1 Percent Predicts Preterm Labor in Blunt Maternal Trauma. 24nd Annual Meeting Of The Society For Maternal-Fetal Medicine, New Orleans La, 2/404 -2/07/04.
      3. Muench M, Baschat A, Kopelman J, Harman Cr. Indomethacin Initiated Before 24 Weeks Of Gestation For The Prevention Of Preterm Birth. 51st Acog-ACM, New Orleans La, April 26-30 2003.
      4. Muench M, Baschat A, Malinow A, Mighty H. The New Spectrum of Disease n the Obstetrical Intensive Care Unit. 23rd Annual Meeting Of The Society For Maternal-Fetal Medicine, San Francisco Ca, Feb 3-8 2003.
      5. Baschat A , Muench M, Kopelman J, Mighty H, Malinow Am. Gravid Hysterectomy:Ten Year Experience At An Academic Referral Center . 23rd Annual Meeting Of The Society For Maternal-Fetal Medicine, San Francisco Ca, Feb 3-8 2003.
      6. Muench, M, Harman C, Baschat A, Alger L, Weiner C. Early Fetal Exposure To Long Term Indomethacin Therapy To Prevent Preterm Delivery: Neonatal Outcome. 22nd Annual Meeting Of The Society For Maternal-Fetal Medic, New Orleans La, 1/14/02-1-19/02.
      7. Muench, M. Harman ,. Reddy, U,. Baschat A, Mighty, H. In Maternal Trauma, Kleihauer Betke Testing Predicts Preterm Labor. 22nd Annual Meeting Of The Society For Maternal-Fetal Medicine, New Orleans La, 1/14/02-1-19/02.
    2. Publications
      1. Baschat AA, Muench MV, Gembruch U, Coronary artery blood flow velocities in various fetal conditions. Ultrasound in Obstetrics & Gynecology. 21(5):426-428, May 2003.
      2. Muench, MV. MD; Baschat, AA. MD; Reddy, UM. MD, MPH; Mighty, HE. MD; Weiner, C P. MD; Scalea, TM. MD; Harman, CR. MD Kleihauer-Betke Testing Is Important in All Cases of Maternal Trauma. Journal of Trauma-Injury Infection & Critical Care. 57(5):1094-1098, November 2004.
      3. Kush, ML. MD; Muench, MV. MD; Harman, CR. MD; Baschat, AA. MD Persistent Fetal Hemoglobin in Maternal Circulation Complicating the Diagnosis of Fetomaternal Hemorrhage. Obstetrics & Gynecology. 105(4):872-874, April 2005.
      4. Muench, MV. MD; Baschat, AA. MD; Dorio, PJ. MD; Mighty, HE. MD Successful Pregnancy Outcome after Splenic Artery Embolization for Blunt Maternal Trauma. Journal of Trauma-Injury Infection & Critical Care. 56(5):1146-1148, May 2004.
      5. Baschat, A. A.; Muench, M. V.; Gembruch, U. Coronary artery blood flow velocities in various fetal conditions. Ultrasound in Obstetrics & Gynecology. 21(5):426-429, May 2003.
  2. Baschat, Ahmet 2003
    1. Presentations
      1. Baschat, Ahmet; Galan, Henry ; Bhide, Amarnath ; Berg, Christoph ; Thilaganathan, Baskaran ; Kush, Michelle ; Oepkes, Dick ; Gembruch, Ulrich ; Weiner, Carl ; Harman, Christopher Determinants Of Intact Survival In Early-Onset Iugr Delivered <32 WEEKS. 24nd Annual Meeting of the Society for Maternal-Fetal Medicine, New Orleans LA, 2/404 -2/07/04.
      2. Baschat, Ahmet ; Galan, Henry ; Bhide, Amarnath ; Berg, Christoph ; Kush, Michelle ; Thilaganathan, Basky ; Oepkes, Dick ; Gemrbuch, Ulrich ; Weiner, Carl ; Harman, Christopher Viability In Early-Onset IUGRr: Is It Time To Reconsider Intervention Thresholds?. 24nd Annual Meeting of the Society for Maternal-Fetal Medicine, New Orleans LA, 2/404 -2/07/04
      3. Baschat, Ahmet ; Guclu, Serkan ; Demir, Namik ; Gembruch, Ulrich ; Weiner, Carl ; Harman, Christopher. Which Venous Doppler Parameter Provides The Most Accurate Prediction Of Acid-Base Status 24nd Annual Meeting of the Society for Maternal-Fetal Medicine, New Orleans LA, 2/4/04 -2/07/04 .
      4. Baschat, Ahmet ; Kush, Michelle ; Harman, Christopher ; Weiner, Carl. Hematologic Indices And Fetal Oxygenation Determine Middle Cerebral Artery Peak Systolic Velocity (Mca-Psv). 24nd Annual Meeting of the Society for Maternal-Fetal Medicine, New Orleans LA, 2/4/04 -2/07/04.
      5. Baschat, A. *; Gembruch, U. +; Weiner, C. P. *; Harman, C. R. * Combining Doppler and biophysical assessment improves prediction of critical perinatal outcomes in growth restricted fetuses (IUGR). 13th Annual World Congres son Ultrasound in Ob and Gyn. Paris France 31 Aug-4 Sep 2003.
      6. Baschat, A. *; Guclu, S. +; Kush, M. L. ++; Gembruch, U. [S]; Weiner, C. P. ++; Harman, C. R. ++ Venous Doppler in the prediction of acid base status at birth - Which vessel, which parameter?. ). 13th Annual World Congres son Ultrasound in Ob and Gyn. Paris France 31 Aug-4 Sep 2003.
      7. Muench MV, Baschat AA, Kopelman J, Harman CR. Indomethacin initiated before 24 weeks of gestation for the prevention of preterm birth. 51st ACOG-ACM, New Orleans LA, April 26-30 2003.
      8. Jenkins CB, Pezzullo JB, Baschat AA, Eglington GS. Fetal growth patterns in triplet gestation. 51st ACOG-ACM, New Orleans LA, April 26-30 2003.
      9. Jenkins CB, Baschat AA, Schruefer JJ. Upper quadrant abnormality detection at time of indicated obstetrics or gynecologic ultrasound. 51st ACOG-ACM, New Orleans LA, April 26-30 2003.
      10. Muench MV, Baschat AA, Malinow AM, Mighty HE. The new spectrum of disease in the obstetrical intensive care unit. 23rd Annual Meeting of the Society for Maternal-Fetal Medicine, San Francisco CA, Feb 3-8 2003.
      11. Baschat AA, Muench MV, Kopelman J, Mighty HE, Malinow AM. Gravid Hysterectomy:Ten Year experience at an academic referral center . 23rd Annual Meeting of the Society for Maternal-Fetal Medicine, San Francisco CA, Feb 3-8 2003.
      12. Baschat AA, Gembruch U, Weiner CP, Harman CR. Combining Doppler and biophysical assessment improves prediction of critical perinatal outcomes. 23rd Annual Meeting of the Society for Maternal-Fetal Medicine, San Francisco CA, Feb 3-8 2003.
      13. Baschat AA, Muench MV, Towbin J, Harman CR, Weiner CP. Seasonal pattern of adenovirus in amniotic fluid. 23rd Annual Meeting of the Society for Maternal-Fetal Medicine, San Francisco CA, Feb 3-8 2003.
      14. Baschat AA, Muench MV, Towbin J, Harman CR, Weiner CP. Prevalence of viruses in amniotic fluid of normal pregnancies in the mid-trimester. 23rd Annual Meeting of the Society for Maternal-Fetal Medicine, San Francisco CA, Feb 3-8 2003.
      15. Baschat, A, Kush M, Weiner C, Harman. Fragmentation hemolysis in fetal growth restriction (IUGR) is not worse when umbilical artery end-diastolic velocity is absent. Society for Maternal-Fetal Medicine, New Orleans LA, 1/14/02-1-19/02.
      16. Baschat, A. Gembruch, U. Weiner, C Harman, C. Precordial venous Doppler provides the best prediction of acidemia and mortality in fetal growth restriction (IUGR). Society for Maternal-Fetal Medicine, New Orleans LA, 1/14/02-1-19/02.
      17. Reddy U, Baschat A, . Towbin J, Harman C, Weiner C .Detection of viral deoxyribonucleic acid in amniotic fluid: Association with fetal malformation and pregnancy abnormalities. Society for Maternal-Fetal Medicine, New Orleans LA, 1/14/02-1-19/02.
      18. Reddy U, Zlatnik M, Baschat A. Towbin, Jeffrey 4. Harman, C, Weiner, C. Detection of viral deoxyribonucleic acid in amniotic fluid: predictor of abnormal pregnancy. Society for Maternal-Fetal Medicine, New Orleans LA, 1/14/02-1-19/02.
      19. Harman C. Baschat A, Gembruch U. Venous Doppler in fetal growth restriction (IUGR): Which vessel? Which parameter? Society for Maternal-Fetal Medicine, New Orleans LA, 1/14/02-1-19/02.
      20. Kush M, Baschat A, Harman C. Sustained hematological consequences in neonatal life are caused by fetal compromise. Society for Maternal-Fetal Medicine, New Orleans LA, 1/14/02-1-19/02
    2. Publications
      1. Baschat, A. A. *; Gembruch, U. +; Weiner, C. P. *; Harman, C. R. * Qualitative venous Doppler waveform analysis improves prediction of critical perinatal outcomes in premature growth-restricted fetuses. Ultrasound in Obstetrics & Gynecology. 22(3):240-245, September 2003.
      2. Makh, D. S. *; Harman, C. R. +; Baschat, A. A. Is Doppler prediction of anemia effective in the growth-restricted fetus?. Ultrasound in Obstetrics & Gynecology. 22(5):489-492, November 2003.
      3. Baschat, A. A. *; Gembruch, U. +; Weiner, C. P. *; Harman, C. R. * Qualitative Venous Doppler waveform analysis improves prediction of critical perinatal outcomes in premature growth-restricted fetuses. Ultrasound in Obstetrics & Gynecology. 22(3):240-245, September 2003.
      4. Baschat, Ahmet A. MD a*; Towbin, Jeffrey MD a; Bowles, Neil E. PhD a; Harman, Christopher R. MD a; Weiner, Carl P. MD a Is adenovirus a fetal pathogen? American Journal of Obstetrics & Gynecology. 189(3):758-763, September 2003.
      5. Baschat AA, Muench MV, Gembruch U, Coronary artery blood flow velocities in various fetal conditions. Ultrasound in Obstetrics & Gynecology. 21(5):426-428, May 2003.
      6. Berg C, Geipel A, Kohl M, Krokowski M, Baschat AA, Germer U, Gembruch U. Prenatal sonographic features of Harlequin ichthyosis. Arch Gynecol Obstet. 2003 Apr;268(1):48-51.
      7. Harman CR, Baschat AA. Comprehensive assessment of fetal wellbeing: which Doppler tests should be performed? Curr Opin Obstet Gynecol. 2003 Apr;15(2):147-57.
      8. Baschat AA, Gembruch U. The cerebroplacental Doppler ratio revisited. Ultrasound Obstet Gynecol. 2003 Feb;21(2):124-7
      9. Kush, ML., Jenkins, C B , Baschat, AA Variable umbilical artery end-diastolic velocity: a possible sign of velamentous cord insertion in monochorionic gestation. Ultrasound in Obstetrics & Gynecology. 21(1):95-96, January 2003.
      10. Baschat AA. Integrated fetal testing in growth restriction: combining multivessel Doppler and biophysical parameters. Ultrasound Obstet Gynecol. 2003 Jan;21(1):1-8.
      11. Baschat AA. Harman CR. Farid G. Chodirker BN. Evans JA. Very low second-trimester maternal serum alpha-fetoprotein: Association with high birth weight. [Journal Article] Obstetrics & Gynecology. 99(4):531-6, 2002 Apr.
      12. Baschat AA. Gembruch U. Viscardi RM. Gortner L. Harman CR. Antenatal prediction of intraventricular hemorrhage in fetal growth restriction: what is the role of Doppler?. [Evaluation Studies. Journal Article] Ultrasound in Obstetrics & Gynecology. 19(4):334-9, 2002 Apr.
      13. Berg C, Baschat AA, Geipel A, Germer U, Smrcek J, Krapp M, Gembruch U. First trimester twin-to-twin transfusion syndrome in a trichorionic quadruplet pregnancy--a diagnostic challenge. Fetal Diagn Ther. 2002 Nov-Dec;17(6):357-61.
      14. Baschat AA, Gembruch U. Evaluation of the fetal coronary circulation. Ultrasound Obstet Gynecol. 2002 Oct;20(4):405-12.
      15. Abello KC, Stewart PA, Baschat AA. Two-dimensional and M-mode echocardiography of the fetal coronary sinus. Ultrasound Obstet Gynecol. 2002 Aug;20(2):137-41.
      16. Krapp M. Baschat AA. Gembruch U. Geipel A. Germer U. Flecainide in the intrauterine treatment of fetal supraventricular tachycardia. Ultrasound in Obstetrics & Gynecology. 19(2):158-64, 2002 Feb.
      17. Baschat AA. Gembruch U. Harman CR. The sequence of changes in Doppler and biophysical parameters as severe fetal growth restriction worsens. Ultrasound in Obstetrics & Gynecology. 18(6):571-7, 2001 Dec.
      18. Baschat AA. Love JC. Stewart PA. Gembruch U. Harman CR. Prenatal diagnosis of ventriculocoronary fistula. Ultrasound in Obstetrics & Gynecology. 18(1):39-43, 2001 Jul.
      19. Smrcek JM. Baschat AA. Germer U. Gloeckner-Hofmann K. Gembruch U. Fetal hydrops and hepatosplenomegaly in the second half of pregnancy: a sign of myeloproliferative disorder in fetuses with trisomy 21. Ultrasound in Obstetrics & Gynecology. 17(5):403-9, 2001 May.
      20. Baschat AA. Harman CR. Antenatal assessment of the growth restricted fetus. Current Opinion in Obstetrics & Gynecology. 13(2):161-8, 2001 Apr.
  3. Kush, Michelle 2004
    1. Presentations
      1. Kush M, Baschat A, Harman C. Sustained hematological consequences in neonatal life are caused by fetal compromise. 22nd Annual Meeting of the Society for Maternal-Fetal Medicine, New Orleans LA, 1/14/02-1-19/02.
      2. Baschat, Ahmet 1; Galan, Henry 2; Bhide, Amarnath 3; Berg, Christoph 4; Thilaganathan, Baskaran 3; Kush, Michelle 1; Oepkes, Dick 5; Gembruch, Ulrich 4; Weiner, Carl 6; Harman, Christopher 1 Determinants Of Intact Survival In Early-Onset Iugr Delivered <32 WEEKS. 24nd Annual Meeting of the Society for Maternal-Fetal Medicine, New Orleans LA, 2/404 -2/07/04.
      3. Baschat, Ahmet 1; Galan, Henry 2; Bhide, Amarnath 3; Berg, Christoph 4; Kush, Michelle 1; Thilaganathan, Basky 3; Oepkes, Dick 5; Gemrbuch, Ulrich 4; Weiner, Carl 6; Harman, Christopher 1 Viability In Early-Onset Iugr: Is It Time To Reconsider Intervention Thresholds?. 24nd Annual Meeting Of The Society For Maternal-Fetal Medicine, New Orleans LA, 2/404 -2/07/04.
      4. Kush, Michelle 1; Baschat, Ahmet 1; Vlastos, Emanuel 2; Gross, Gil 2; Harman, Christopher 1; Weiner, Carl 3 Acute Effects Of Intrauterine Transfusion On Fetal Middle Cerebral Artery Peak Systolic Velocity(Mca-Psv). 24nd Annual Meeting Of The Society For Maternal-Fetal Medicine, New Orleans LA, 2/40/4 -2/07/04.
      5. Kush, Michelle 1; Baschat, Ahmet 1; Coke, Gary 2; Muench, Michael 3; Mighty, Hugh 4; Malinow, Andrew 5; Kopelman, Jerome 6; Harman, Christopher 1; Weiner, Carl 7 Morbid Obesity Adversely Impacts Cesarean Delivery. 24nd Annual Meeting Of The Society For Maternal-Fetal Medicine, New Orleans LA, 2/4/04 -2/07/04.
      6. Baschat, Ahmet 1; Kush, Michelle 1; Harman, Christopher 1; Weiner, Carl 2 Hematologic Indices And Fetal Oxygenation Determine Middle Cerebral Artery Peak Systolic Velocity (Mca-Psv). 24nd Annual Meeting Of The Society For Maternal-Fetal Medicine, New Orleans LA, 2/4/04 -2/07/04.
      7. Kush M, Baschat A, Harman C. Sustained hematological consequences in neonatal life are caused by fetal compromise. . 22nd Annual Meeting of the Society for Maternal-Fetal Medicine, New Orleans LA, 1/14/02-1-19/02.
      8. Baschat A, Hashmi N, Kush M, Viscardi R, Weiner C, Harman C. Fetal Doppler in IUGR predicts longterm neurodevelopment. . 25nd Annual Meeting of the Society for Maternal-Fetal Medicine, Reno NV, 2/7/05 -2/12/05.
      9. Kush M, Harman C, Baschat A. Intrauterine growth restriction and neonatal hypothyroidism. . 25nd Annual Meeting of the Society for Maternal-Fetal Medicine, Reno NV, 2/7/05 -2/12/05.
      10. Baschat A, Galan H, Bhide A, Berg C, Kush M, Oepkes D, Thilaganathan B, Gembruch U, Harman C. Doppler assessment and biophysical profile in growth restricted fetuses (IUGR): interaction of test parameters. 25nd Annual Meeting of the Society for Maternal-Fetal Medicine, Reno NV, 2/7/05 -2/12/05.
      11. Baschat A, Bilardo C, Germer U, Hartung J, Rigano S, Berg C, Kush M, Bhide A, Galan H, Thilaganathan B, Ferrazzi E, Hecher K, Gembruch U, Weiner C, Harman C. Thresholds for intervention in severe early onset growth restriction (IUGR). 25nd Annual Meeting of the Society for Maternal-Fetal Medicine, Reno NV, 2/7/05 -2/12/05.
      12. Kush M, Baschat A, Weiner C, Harman C. When should you investigate middle cerebral artery Doppler? 25nd Annual Meeting of the Society for Maternal-Fetal Medicine, Reno NV, 2/7/05 -2/12/05.
      13. Baschat, Ahmet 1; Kush, Michelle 1; Moyano, Dolores 2; Turan, Sifa 3; Berg, Christoph 4; Bhide, Amarnath 5; Thilaganathan, Basky 5; Gembruch, Ulrich 4; Bower, Sarah 3; Nicolaides, Kypros 3; Harman, Christopher 1 Computerized Fetal Heart Rate Analysis (Cctg) For Prediction Of Acidemia In Fetal Growth Restriction (IUGR): 320. 25nd Annual Meeting of the Society for Maternal-Fetal Medicine, Reno NV, 2/7/05 -2/12/05.
      14. Baschat, A. 1; Galan, H. L. 2; Bhide, A. 3; Berg, C. 4; Kush, M. L. 1; Oepkes, D. 5; Thilaganathan, B. 3; Gembruch, U. 4 The relationship of Doppler and biophysical parameters in growth restricted fetuses (IUGR): P10.06. Ultrasound in Obstetrics & Gynecology. Special Issue: 15th World Congress on Ultrasound in Obstetrics and Gynecology. 26(4):440, September 2005.
      15. Baschat, A. 1; Bilardo, C. 2; Germer, U. 3; Hartung, J. 4; Rigano, S. 5; Berg, C. 6; Kush, M. L. 1; Bhide, A. 7; Galan, H. L. 8; Thilaganathan, B. 7; Ferrazzi, E. 5; Hecher, K. 9; Gembruch, U. 6; Weiner, C. P. 1; Harman, C. R. 1 Intervention thresholds for severe early onset growth restriction (IUGR): OC27.04. Ultrasound in Obstetrics & Gynecology. Special Issue: 15th World Congress on Ultrasound in Obstetrics and Gynecology. 26(4):353, September 2005.
      16. Baschat, A.; Hashmi, N; Kush, M. L.; Viscardi, R.; Harman, C. R. Relationship between prenatal Doppler findings and neurodevelopmental outcome at 2 years of age in intrauterine growth restriction (IUGR): OC24.04. Ultrasound in Obstetrics & Gynecology. Special Issue: 15th World Congress on Ultrasound in Obstetrics and Gynecology. 26(4):348, September 2005.
    2. Publications
      1. Kush, ML., Jenkins, C B , Baschat, AA Variable umbilical artery end-diastolic velocity: a possible sign of velamentous cord insertion in monochorionic gestation. Ultrasound in Obstetrics & Gynecology. 21(1):95-96, January 2003.
      2. Kush ML, Weiner CP, Christopher R. Harman, and Ahmet A. Baschat.Lethal Progression of a Fetal Intracranial Arteriovenous Malformation
        J Ultrasound Med 2003 22: 645-648.
      3. Baschat AA, Guclu S, Kush ML, Gembruch U, Weiner CP, Harman CR. Venous Doppler in the prediction of acid-base status of growth-restricted fetuses with elevated placental blood flow resistance. American Journal of Obstetrics and Gynecology. 2004. 191: (1):277-84.
      4. Kush ML, Muench MV, Harman CR, Baschat AA. Persistent fetal hemoglobin in maternal circulation complicating the diagnosis of fetomaternal he.morrhage. Obstet Gynecol. 2005;105(4):872-4.
      5. Kush, Michelle L. MD; Muench, Michael V. MD; Harman, Christopher R. MD; Baschat, Ahmet A. MD. Persistent Fetal Hemoglobin in Maternal Circulation Complicating the Diagnosis of Fetomaternal Hemorrhage. Obstetrics & Gynecology. 105(4):872-874, April 2005
  4. Oh, Chien 2007
    1. Presentations
      1. i) Oh Chien; Dong, Yafeng; Thompson, Loren. Chronic Maternal Hypoxia Increases Both Total Glutathione And - Glutamylcysteine Synthetase (GCS) Expression In Fetal Guinea Pig Liver: 605. 26th Annual Meeting of the Society for Maternal-Fetal Medicine. Fontainebleau Hotel Miami Beach, FL 30 January 2006 - 04 February 2006.

      2. Oh, Chien; Baschat, Ahmet ; Harman, Christopher. Even In Embryos With Normal Nuchal Translucency (Nt), An Abnormal Ductus Venosus (DV) May Signify Anomaly: 540. 26th Annual Meeting of the Society for Maternal-Fetal Medicine. Fontainebleau Hotel Miami Beach, FL 30 January 2006 - 04 February 2006
    2. Publications
      1. Oh Chien; Dong, Yafeng; Harman Chrstopher, Mighty, Hugh, Kopelman Jerome, Tompson, Loren. Chronic Hypoxia Differentiallly Increases Glutathione Content and - Glutamylcysteine Synthetase Expression In Fetal Guinea Pig Organs. – In press
  5. Manogura, Anita 2007
    1. Presentations
      1. Manogura , Anita: Kush, Michelle; Moyano, Dolores: Turan, Sifa; Bilardo, Caterina M.; Germer, Ute; Hartung, John; Rigano, Serena; Mueller, Thomas Berg, Christoph: Bhide, Amarnath; Oepkes, Dick; Thilaganathan, Baskaran; Galan, Henry; Ferrazi, Enrico ; Hecher, Kurt; Bower, Sarah ; Nicolaides, Kypros ; Harman, Christopher; Gembruch, Ulrich; Baschat, Ahmet. Predictors Of Necrotizing Entercolitis (NEC) In Fetal Growth Restriction (IUGR): 196. 26th Annual Meeting Of The Society For Maternal-Fetal Medicine. Fontainebleau Hotel Miami Beach, Fl 30 January 2006 - 04 February 2006.

      2. Baschat, Ahmet; Kush, Michelle; Manogura, Anita; Moyano, Dolores; Turan, Sifa; Germer, Ute: Berg, Christoph; Bhide, Amarnath; Oepkes, Dick; Thilaganathan, Baskaran; Galan, Henry; Bower, Sarah; Nicolaides, Kypros; Gembruch, Ulrich; Harman, Christopher. Integrated Fetal Testing Is The Most Accurate Predictor Of Perinatal Outcome In Intrauterine Growth Restriction (IUGR): 79. American Journal of Obstetrics & Gynecology. 193 Supplement 6:S35, February 2006

Program Faculty and Fellow Publications 2004-2006

  1. Baschat, Ahmet Alexander; Harman, Chris R. Venous Doppler in the assessment of fetal cardiovascular status. Current Opinion in Obstetrics & Gynecology. 18(2):156-163, April 2006.

  2. Kush ML, Gortner L, Harman CR, Baschat AA. Sustained hematological consequences in the first week of neonatal life secondary to placental dysfunction. Early Hum Dev. 2006 Jan;82(1):67-72. Epub 2005 Sep 28.

  3. Baschat, A. A.; Galan, H. L. Bhide, A., Berg, C. Kush, M. L,; Oepkes, D. Thilaganathan, B., Gembruch, U., Harman, C. R. * Doppler and biophysical assessment in growth restricted fetuses: distribution of test results. Ultrasound in Obstetrics & Gynecology. 27(1):41-47, January 2006.

  4. Reddy UM, Baschat AA, Zlatnik MG, Towbin JA, Harman CR, Weiner CP.. Detection of viral deoxyribonucleic acid in amniotic fluid: association with fetal malformation and pregnancy abnormalities.Fetal Diagn Ther. 2005 May-Jun;20(3):203-7.

  5. Weiner C.P., Reddy U.M., Baschat A.A., Zlatnik M., Harman C.R., Towbin J.. Detection of viral deoxyribonucleic acid in amniotic fluid: association with fetal malformation and pregnancy abnormalities. Fetal Diagnosis and Therapy 20:203-207, 2005.

  6. Kush, Michelle L. MD; Muench, Michael V. MD; Harman, Christopher R. MD; Baschat, Ahmet A. MD. Persistent Fetal Hemoglobin in Maternal Circulation Complicating the Diagnosis of Fetomaternal Hemorrhage. Obstetrics & Gynecology. 105(4):872-874, April 2005.

  7. Baschat AA, Harman CR, Gembruch U. Haematological consequences of placental insufficiency. Arch Dis Child Fetal Neonatal Ed. 2004;89(1):F94.

  8. Baschat AA, Guclu S, Kush M, Gembruch U, Weiner C, Harman C. Venous Doppler in the prediction of acid-base status of growth-restricted fetuses with elevated placental blood flow resistance. Am J Obstet Gynecol. 2004;191(1):277.

  9. Muench MV, Baschat AA, Reddy UM, Mighty HE, Weiner CP, Harman CR. Kleihauer Betke testing is important in all cases of maternal trauma. J Trauma. 2004 Nov;57(5):1094-8.

  10. Baschat AA, Harman CR, Gembruch U. Haematological consequences of placental insufficiency. Arch Dis Child Fetal Neonatal Ed. 2004;89(1):

  11. Whyte H, Hannah ME, Saigal S. Hannah WJ, Hewson S, Amankwah K, Cheng M, Gafni A, Guselle P, Helewa M, Hodnett E, Hutton E, Kung R, McKay D, Ross S. Willan A, Term Breech Trial Collaborative Group (including Alger L). Outcomes of children at 2 years after planned cesarean vs planned vaginal delivery for breech presentation at term: the International Randomized Term Breech Trial. Am J Obstet Gynecol. 191: 864-71, 2004.

  12. Hannah ME, Whyte H, Hannah WJ, Hewson S, Amankwah K, Cheng M, Gafni A, Guselle P, Helewa M, HOdnett E, Hutton E, Kung R, McKay D, Ross S, Saigal S, Willan A, Term Breech Trial Collaborative Group (including Alger L). Maternal outcomes at 2 years after planned cesarean vs planned vaginal delivery for breech presentation at term: the International Randomized Term Breech Trial. Am J Obstet Gynecol. 191: 917-27, 2004.

  13. Su M, Hannah W J, Willan A, Ross S, Hannah M E, Term Breech Trial Collaborative Group (including Alger L). Planned cesarean section decreases the risk of adverse perinatal outcome due to both labour and delivery complications in the Term Breech Trial. Br J Obstet Gynaecol. 2004 Oct;111(10):1065-74.

  14. Guclu, S. ; Gol, M. ; Saygili, U. ; Demir, N. ; Sezer, O. ; Baschat, A. A. Nifedipine therapy for preterm labor: effects on placental, fetal cerebral and atrioventricular Doppler parameters in the first 48 hours. Ultrasound in Obstetrics & Gynecology. 27(4):403-408, April 2006.

  15. Baschat, A. A. The fetal circulation and essential organs - a new twist to an old tale. Ultrasound in Obstetrics & Gynecology. 27(4):349-354, April 2006.

  16. Berg, C; Geipel, A., Kohl, T.; Smrcek, J., Germer, U., Baschat, A. A., Hansmann, M.; Gembruch, U. Fetal echocardiographic evaluation of atrial morphology and the prediction of laterality in cases of heterotaxy syndromes. Ultrasound in Obstetrics & Gynecology. 26(5):538-545, October 2005.

  17. Berg, C; Geipel, A.; Kohl, T. ; Breuer, J.; Germer, U.; Krapp, M., Baschat, A. A; Hansmann, M; Gembruch, U. Atrioventricular block detected in fetal life: associated anomalies and potential prognostic markers. Ultrasound in Obstetrics & Gynecology. 26(1):4-15, July 2005.

  18. Guclu, S; Saygili, U; Dogan, E; Demir, N; Baschat, A A. The Short-Term Effect of Nifedipine Tocolysis on Placental, Fetal Cerebral, and Atrioventricular Doppler Waveforms. Obstetrical & Gynecological Survey. 60(5):287-289, May 2005.

  19. Reddy UM, Baschat AA, Zlatnik MG, Towbin JA, Harman CR, Weiner CP.. Detection of viral deoxyribonucleic acid in amniotic fluid: association with fetal malformation and pregnancy abnormalities. Fetal Diagn Ther. 2005 May-Jun;20(3):203-7.

  20. Weiner C.P., Reddy U.M., Baschat A.A., Zlatnik M., Harman C.R., Towbin J.. Detection of viral deoxyribonucleic acid in amniotic fluid: association with fetal malformation and pregnancy abnormalities. Fetal Diagnosis and Therapy 20:203-207, 2005.

  21. Guclu, S., Saygili, U, Dogan, E., Demir, N., Baschat, A. A. .The short-term effect of nifedipine tocolysis on placental, fetal cerebral and atrioventricular Doppler waveforms. Ultrasound in Obstetrics & Gynecology. 24(7):761-765, December 2004.

  22. Guclu, S., Saygili, U, Dogan, E., Demir, N., Baschat, A. A + The short-term effect of nifedipine tocolysis on placental, fetal cerebral and atrioventricular Doppler waveforms. Ultrasound in Obstetrics & Gynecology. 24(7):761-765, December 2004.

  23. Baschat, Ahmet A. MD, Guclu, Serkan MD, Kush, Michelle L. MD,Gembruch, Ulrich MD, Weiner, Carl P. MD, Harman, Chris R. MD Venous Doppler in the prediction of acid-base status of growth-restricted fetuses with elevated placental blood flow resistance. American Journal of Obstetrics & Gynecology. 191(1):277-284, July 2004.

  24. Baschat, A. A. Doppler application in the delivery timing of the preterm growth-restricted fetus: another step in the right direction. Ultrasound in Obstetrics & Gynecology. 23(2):111-118, February 2004.

  25. Muench M.V., Baschat A.A., Reddy U.M., Mighty H.E., Weiner C.P., Scalea T.M., Harman C.R. Kleihauer-Betke Testing Is Important in All Cases of Maternal Trauma. J Trauma; 57:1094-1098, 2004.

  26. Baschat, A. A. *; Gembruch, U. +; Weiner, C. P. *; Harman, C. R. * Qualitative Venous Doppler Waveform Analysis Improves Prediction Of Critical Perinatal Outcomes In Premature Growth-Restricted Fetuses. Ultrasound In Obstetrics & Gynecology. 22(3):240-245, September 2003.

  27. Baschat, Ahmet A. MD; Towbin, Jeffrey MD, Bowles, Neil E. PhD a; Harman, Christopher R. MD a; Weiner, Carl P. MD a Is adenovirus a fetal pathogen? American Journal of Obstetrics & Gynecology. 189(3):758-763, September 2003.

  28. Baschat, A. A., Gembruch, U.,Weiner, C. P. Harman, C. R. Qualitative venous Doppler waveform analysis improves prediction of critical perinatal outcomes in premature growth-restricted fetuses. Ultrasound in Obstetrics & Gynecology. 22(3):240-245, September 2003

  29. Muench, Michael V. MD; Baschat, Ahmet A. MD; Dorio, Paul J. MD; Mighty, Hugh E. MD Successful Pregnancy Outcome after Splenic Artery Embolization for Blunt Maternal Trauma. Journal of Trauma-Injury Infection & Critical Care. 56(5):1146-1148, May 2004

  30. Coke GA. Baschat AA. Mighty HE. Malinow AM. Maternal cardiac arrest associated with attempted fetal injection of potassium chloride. International Journal of Obstetric Anesthesia. 13(4):287-90, 2004 Oct.

  31. Baschat AA, Muench MV, Mighty HE, Harman CR. Successful intrauterine management of severe feto-fetal transfusion in a monochorionic triplet pregnancy using bipolar umbilical cord coagulation. Fetal Diagn Ther. 2003 Nov-Dec;18(6):397-400.

  32. Rust OA, Atlas RO, Kimmel S, Roberts WE, Hess LW. Does the presence of a funnel increase the risk of adverse perinatal outcome in a patient with a short cervix? Am J Obstet Gynecol. 2005 Apr;192(4):1060-6.

  33. Baschat AA, Galan HL, Bhide A, Berg C, Kush ML, Oepkes D, Thilaganathan B, Gembruch U, Harman CR.Doppler and biophysical assessment in growth restricted fetuses: distribution of test results. Ultrasound Obstet Gynecol. 2006 Jan;27(1):41-7.

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