Bupivacaine/lidocaine (Injection)


Bupivacaine (bue-PIV-a-kane), Lidocaine (LYE-doe-kane)

Causes numbness (loss of feeling) to your eye, and may keep your eye from moving for a short time. Used as an anesthetic during certain medical treatments of the eye.

Brand Name(s)

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not receive this medicine if you have had an allergic reaction to bupivacaine, lidocaine, or certain other types of local anesthetic (numbing medicine). You should not receive this medicine if you have certain heart rhythm problems such as Wolff-Parkinson-White syndrome, Stokes-Adams syndrome, or severe heart block, unless you have a pacemaker.

How to Use This Medicine


  • A nurse or other trained health professional will give you this medicine. This medicine is injected with a needle into one or more areas around your eye.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are taking heart or blood pressure medicine such as digoxin (Lanoxin®), atenolol (Tenormin®), propranolol (Inderal®), or metoprolol (Lopressor®). Make sure your doctor knows about any other medicine you have used recently.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breast feeding. You may need to stop breast feeding for a short time after receiving this medicine.
  • Make sure your doctor knows if you have high blood pressure, low blood pressure, or other circulation problems. Tell your doctor if you have heart problems, such as congestive heart failure or heart rhythm problems. Make sure your doctor knows if you have liver disease, or any other health problems or drug allergies.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Dizziness, drowsiness, confusion (trouble thinking), seizures (convulsions), or fainting.
  • Nausea or vomiting.
  • Loss of feeling or movement to your eye that lasts longer than your doctor told you to expect.
  • Loss of feeling or movement that happens somewhere else in your body other than the area that was numbed for treatment.
  • Restlessness, anxiety.
  • Ringing in the ears.
  • Sudden or severe headache, or problems with vision, speech, or walking.
  • Tremors, shaking, or chills.
  • Trouble urinating, or new problems controlling when you urinate or have a bowel movement.
  • Uneven, pounding, fast, or slow heartbeats.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Version Info

  • Last Reviewed on 06/12/2013

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