Indications and Results

More than 25 years of pre-clinical research and clinical practice document the success of the Gamma Knife.

The more than 41,000 adults and children who have undergone Gamma Knife treatment have experienced medical benefits, attesting to the long-term safety and efficacy of this clinical tool.

The Gamma Knife is proven effective in the treatment of a range of conditions, including:

  • Metastatic tumors

  • Small to medium volume intracranial arteriovenous malformations (AVM)

  • Meningiomas

  • Acoustic neuromas

  • Gliomas

  • Pituitary adenomas

  • Craniopharyngiomas

  • Skull base tumors

  • Pineal region tumors

  • Trigeminal neuralgia

Read some of our Patient Success Stories.

Especially significant, Gamma Knife treatment has helped patients with tumors once deemed inoperable due to location; patients considered at high risk for conventional surgery due to medical condition; patients with tumors recurrent after surgery and/or radiation therapy; and patients whose tumors were not totally removed by surgery.

Metastatic Tumors: Eighty percent of more than 7,300 patients with metastatic/tumors have shown growth arrest, decrease in size, or complete eradication after Gamma Knife radiosurgery.

Benign and Malignant Intracranial Tumors: Gamma Knife treatment has proven effective in the treatment of glial, meningeal, neuronal, and pituitary tumors. In a study of patients with acoustic neuromas, Gamma Knife treatment was documented 90 percent effective with patients experiencing either decrease in tumor size or arrested growth. In 36 percent of these cases, preoperative hearing levels were preserved on a long-term basis. Cushing's disease was eliminated in 80 percent of the patients with pituitary tumors treated with the Gamma Knife.

Arteriovenous malformations: AVMs are life-threatening congenital tangles of blood vessels in the brain that can cause seizures and hemorrhage. Among the more than 11,000 patients treated with the Gamma Knife for AVMs and thus far documented, 85 percent experienced total eradication of their malformations within two years of treatment.

Functional Disorders and Pain: Gamma Knife treatment is sometimes useful for the treatment of trigeminal neuralgia. Worldwide, the procedure has helped patients with Parkinson's Disease, epilepsy, and intractable pain such as trigeminal neuralgia.

The University of Maryland Gamma Knife team has treated more than 2,500 patients since the center opened in 1992.

The team meets at least weekly, so they can ensure that each patient receives an immediate evaluation.

To schedule a consultation with the University of Maryland Gamma Knife Center team, please call 410-328-6080.